European Perspective on Multiple Myeloma Treatment Strategies: Update Following Recent Congresses

被引：50

作者：

Ludwig, Heinz ^{[1
]}

Avet-Loiseau, Herve ^{[2
]}

Blade, Joan ^{[3
]}

Boccadoro, Mario ^{[4
]}

Cavenagh, Jamie ^{[5
]}

Cavo, Michele ^{[6
]}

Davies, Faith ^{[7
]}

de la Rubia, Javier ^{[8
]}

Delimpasi, Sosana ^{[11
]}

Dimopoulos, Meletios ^{[9
]}

Drach, Johannes ^{[10
]}

Einsele, Hermann ^{[12
]}

Facon, Thierry ^{[13
]}

Goldschmidt, Hartmut ^{[14
]}

Hess, Urs ^{[15
]}

Mellqvist, Ulf-Henrik ^{[16
]}

Moreau, Philippe ^{[17
]}

San-Miguel, Jesus ^{[18
]}

Sondergeld, Pia ^{[19
]}

Sonneveld, Pieter ^{[20
]}

Udvardy, Miklos ^{[21
]}

Palumbo, Antonio ^{[4
]}

机构：

[1] Wilhelminenspital Stadt Wien, Ctr Oncol & Hematol, Dept Med 1, A-1160 Vienna, Austria

[2] Inst Biol, Hematol Lab, Nantes, France

[3] IDIBAPS, Hosp Clin, Dept Hematol, Barcelona, Spain

[4] Univ Turin, Div Ematol, Azienda Osped S Giovanni Battista, Osped Molinette, Turin, Italy

[5] St Bartholomews Hosp, Dept Hematol, London, England

[6] Inst Hematol & Med Oncol, Bologna, Italy

[7] Royal Marsden Hosp, Inst Canc Res, London SW3 6JJ, England

[8] Univ Hosp La Fe, Hematol Serv, Valencia, Spain

[9] Univ Athens, Sch Med, Dept Clin Therapeut, GR-11527 Athens, Greece

[10] Univ Clin, Dept Oncol, Vienna, Austria

[11] Evangelismos Hosp Hematol & Bone Marrow Transplan, Athens, Greece

[12] Med Klin & Poliklin 2, Universitatsklinik Wurzburg, Wurzburg, Germany

[13] CHU, Serv Hematol, Lille, France

[14] Heidelberg Univ, Dept Internal Med 5, Heidelberg, Germany

[15] Kantonsspital, Div Hematol Oncol, St Gallen, Switzerland

[16] Sahlgrens Univ Hosp, Dept Hematol, Gothenburg, Sweden

[17] Univ Hosp, Nantes, France

[18] Hosp Univ Salamanca, Hematol Serv, CIC, IBMCC USAL CSIC, Salamanca, Spain

[19] Ammonite Syst Ltd, Faringdon, England

[20] Erasmus MC, Dept Hematol, Rotterdam, Netherlands

[21] Med & Hlth Sci Ctr, Inst Med, Debrecen, Hungary

来源：

ONCOLOGIST | 2012年 / 17卷 / 05期

关键词：

Multiple myeloma; Novel agents; Thalidomide; Bortezomib; Lenalidomide; STEM-CELL TRANSPLANTATION; BORTEZOMIB PLUS DEXAMETHASONE; RANDOMIZED PHASE-III; HIGH-DOSE MELPHALAN; PERIPHERAL NEUROPATHY; ELDERLY-PATIENTS; INITIAL THERAPY; MOLECULAR CLASSIFICATION; INTERGROUPE FRANCOPHONE; CONSOLIDATION THERAPY;

D O I：

10.1634/theoncologist.2011-0391

中图分类号：

R73 [肿瘤学];

学科分类号：

100214 ;

摘要：

The management of multiple myeloma has undergone profound changes over the recent past as a result of advances in our understanding of the disease biology as well as improvements in treatment and supportive care strategies. Notably, recent years have seen a surge in studies incorporating the novel agents thalidomide, bortezomib, and lenalidomide into treatment for different disease stages and across different patient groups. This article presents an update to a previous review of European treatment practices and is based on discussions during an expert meeting that was convened to review novel agent data published or presented at medical meetings until the end of 2011 and to assess their impact on treatment strategies. The Oncologist 2012;17:592-606

引用

页码：592 / 606

页数：15

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