Multiple Symmetric Lipomatosis

被引:9
作者
da Silva, Rodrigo Gomes [1 ]
Braganca, Renan Detoffol
Costa, Carolina Ribeiro
de Melo, Lorena Torres
Telles, Rosa Weiss
Silva, Luciana Costa
机构
[1] Univ Fed Minas Gerais, Hosp Clin, Sch Med, BR-30130100 Belo Horizonte, MG, Brazil
关键词
MADELUNGS-DISEASE; LAUNOIS-BENSAUDE; POLYNEUROPATHY; INVOLVEMENT; DIAGNOSIS; OBESITY;
D O I
10.2310/7750.2011.10026
中图分类号
R75 [皮肤病学与性病学];
学科分类号
100206 ;
摘要
Background: Multiple symmetric lipomatosis (MSL) is a relatively uncommon entity of unknown etiology characterized by symmetrically subcutaneous accumulation of nonencapsulated adipose tissue. Approximately 200 to 300 cases have been published. Objectives: The aims of this article are to report the case of a 58-year-old Brazilian patient with MSL and provide a comprehensive overview of the current concepts concerning this disease. Methods: Our search yielded 28 articles on MSL, including case reports and reviews of the literature. Results: MSL predominantly affects Mediterranean males with a history of chronic alcohol abuse. It is usually asymptomatic and may be associated with diabetes mellitus, hyperlipidemia, hyperuricemia, macrocytic anemia, and oral cancer. Surgical resection is the best treatment option. Conclusion: The case reported is a classic presentation of MSL; however, it is particularly uncommon owing to the association with immune thrombocytopenic purpura. This association has been described only once in the medical literature.
引用
收藏
页码:230 / 235
页数:6
相关论文
共 30 条
[21]   Multiple symmetric lipomatosis may be the consequence of defective noradrenergic modulation of proliferation and differentiation of brown fat cells [J].
Nisoli, E ;
Regianini, L ;
Briscini, L ;
Bulbarelli, A ;
Busetto, L ;
Coin, A ;
Enzi, G ;
Carruba, M .
JOURNAL OF PATHOLOGY, 2002, 198 (03) :378-387
[22]   BENIGN SYMMETRICAL LIPOMATOSIS LAUNOIS-BENSAUDE - REPORT OF 10 CASES AND REVIEW OF THE LITERATURE [J].
RUZICKA, T ;
VIELUF, D ;
LANDTHALER, M ;
BRAUNFALCO, O .
JOURNAL OF THE AMERICAN ACADEMY OF DERMATOLOGY, 1987, 17 (04) :663-674
[23]   BENIGN SYMMETRICAL LIPOMATOSIS WITH MEDIASTINAL INVOLVEMENT AND GROWTH-RETARDATION [J].
SANROMAN, JF ;
GONZALEZ, FD ;
CAMPO, FJR .
JOURNAL OF ORAL AND MAXILLOFACIAL SURGERY, 1992, 50 (03) :299-301
[24]   Launois-Bensaude's disease: About 17 cases [J].
Semenou, D. ;
Coeugniet, E. ;
Segard, M. ;
Martinot-Duquennoy, V. ;
Delaporte, E. .
ANNALES DE CHIRURGIE PLASTIQUE ESTHETIQUE, 2008, 53 (05) :399-407
[25]  
Stoll C, 1996, ANN GENET-PARIS, V39, P193
[26]   Long-term results following surgical treatment of benign symmetric lipomatosis (BSL) [J].
Ujpál, M ;
Németh, ZS ;
Reichwein, A ;
Szabó, GY .
INTERNATIONAL JOURNAL OF ORAL AND MAXILLOFACIAL SURGERY, 2001, 30 (06) :479-483
[27]   Madelung's disease involving the tongue [J].
Vargas-Díez, E ;
Daudén, E ;
Jones-Caballero, M ;
García-Díez, A .
JOURNAL OF THE AMERICAN ACADEMY OF DERMATOLOGY, 2000, 42 (03) :511-513
[28]  
Villaverde V, 1997, An Med Interna, V14, P431
[29]  
Wu Chung-Shin, 2004, Kaohsiung Journal of Medical Sciences, V20, P133
[30]   Madelung disease: manifestations of CT and MR imaging [J].
Zhang, Xin-yu ;
Li, Ning-yi ;
Xiao, Wen-lin .
ORAL SURGERY ORAL MEDICINE ORAL PATHOLOGY ORAL RADIOLOGY AND ENDODONTOLOGY, 2008, 105 (05) :E57-E64