Electrocardiography and Doppler echocardiography in secondary (AA) amyloidosis

Whereas cardiac involvement may occur with secondary amyloidosis, significant deposition of amyloid in the heart, to the extent seen in primary amyloidosis, is rare. Of 44 patients examined with secondary amyloidosis, 7 (16%) had electrocardiographic and only 2 (5%) had echocardiographic features compatible with cardiac amyloidosis; neither patient had compromised cardiac function or died of cardiac causes.