In vivo studies of a platinum(II) metallointercalator

被引：37

作者：

Fisher, Dianne M. ^{[1
]}

Fenton, Ronald R. ^{[1
]}

Aldrich-Wright, Janice R. ^{[2
]}

机构：

[1] Univ Sydney, Ctr Heavy Met Res, Sch Chem, Sydney, NSW 2006, Australia

[2] Univ Western Sydney, Sch Biomed & Hlth Sci, Penrith, NSW 1797, Australia

来源：

CHEMICAL COMMUNICATIONS | 2008年 / 43期

关键词：

D O I：

10.1039/b811723c

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

An in vivo study for determining the toxicity and efficacy of [Pt(S,S-dach)(phen)Cl-2 center dot 1.5H(2)O center dot 0.5HCl (PHENSS) in female Specific Pathogen Free (SPF) Swiss nude mice bearing PC3 tumour xenografts revealed PHENSS to be non-toxic and effective in decreasing tumour growth.

引用

页码：5613 / 5615

页数：3

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