Challenges in applying microarrays to environmental studies

被引:128
作者
Zhou, JZ [1 ]
Thompson, DK [1 ]
机构
[1] Oak Ridge Natl Lab, Div Environm Sci, Oak Ridge, TN 37831 USA
关键词
D O I
10.1016/S0958-1669(02)00319-1
中图分类号
Q5 [生物化学];
学科分类号
071010 ; 081704 ;
摘要
Although DNA microarray technology has been used successfully to analyze global gene expression in pure cultures, it has not been rigorously tested and evaluated within the context of complex environmental samples. Adapting microarray hybridization for use in environmental studies faces several challenges associated with specificity, sensitivity and quantitation.
引用
收藏
页码:204 / 207
页数:4
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