Contraceptive adherence among HIV-infected women in Malawi: a randomized controlled trial of the copper intrauterine device and depot medroxyprogesterone acetate

被引:17
作者
Haddad, Lisa B. [1 ]
Cwiak, Carrie [1 ]
Jamieson, Denise J. [1 ]
Feldacker, Caryl [2 ,3 ]
Tweya, Hannock [2 ]
Hosseinipour, Mina [4 ,5 ,6 ]
Hoffman, Irving [4 ]
Bryant, Amy G. [4 ]
Stuart, Gretchen S. [4 ]
Noah, Isaac [2 ]
Mulundila, Linly [2 ]
Samala, Bernadette [2 ]
Mayne, Patrick [7 ]
Phiri, Sam [2 ]
机构
[1] Emory Univ, Dept Gynecol & Obstet, Atlanta, GA 30322 USA
[2] Lighthouse Trust, Lilongwe, Malawi
[3] Univ Washington, I TECH, Seattle, WA 98195 USA
[4] Univ N Carolina, Chapel Hill, NC USA
[5] UNC Project, Lilongwe, Malawi
[6] Minist Hlth, Reprod Hlth Serv, Lilongwe, Malawi
[7] Brown Univ, Dept Sociol, Providence, RI 02912 USA
关键词
HIV; Contraception; Adherence; IUD; Depot medroxyprogesterone acetate; DMPA; HORMONAL CONTRACEPTIVES; DISCONTINUATION; CONTINUATION; ACQUISITION; USERS; RISK;
D O I
10.1016/j.contraception.2013.08.006
中图分类号
R71 [妇产科学];
学科分类号
100211 ;
摘要
Objective: To evaluate contraceptive adherence to the copper intrauterine device (Cu-IUD) and the injectable depot medroxyprogesterone acetate (DMPA) among women with HIV in Lilongwe, Malawi. Methods: We randomized 200 HTV-infected women on highly active antiretroviral therapy (HAART) to either the Cu-IUD or DMPA and followed these women prospectively, evaluating adherence and factors associated with nonadherence. Results: There was no difference in contraceptive adherence: 68% of Cu-IUD and 65% of DMPA users were adherent at 48 weeks. Receiving first-choice contraceptive was not associated with adherence. Women commonly cited partner's disapproval as an indication for discontinuation. Women who experienced heavy menstruation and first-time contraceptive users were more likely to be nonadherent. Among ongoing users at study conclusion, 95% were happy with their method, and 98% would recommend their method to a friend. Conclusion: Contraceptive adherence between the Cu-IUD and DMPA was similar at 1 year. With similar adherence and similar high rates of satisfaction among users of both methods at 1 year, the Cu-RID offers a hormone-free alternative to DMPA. Implications: Adherence to the Cu-IUD and DMPA is similar at 1 year among HIV-infected women on HAART in a randomized controlled trial. Despite high method satisfaction, partner disapproval and heavy bleeding contribute to reduced adherence. Receiving a method that differs from participant's first-choice method did not influence adherence. (C) 2013 Elsevier Inc. All rights reserved.
引用
收藏
页码:737 / 743
页数:7
相关论文
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