A Silent Biomarker for Reflux Aspiration or an Active Player in Extra-Esophageal Mucosal Injury?

被引:12
作者
Kahrilas, Peter J. [1 ]
Kia, Leila [1 ]
机构
[1] Northwestern Univ, Dept Med, Feinberg Sch Med, Chicago, IL 60611 USA
关键词
PEPSIN; ACID;
D O I
10.1378/chest.15-0506
中图分类号
R4 [临床医学];
学科分类号
1002 ; 100602 ;
摘要
引用
收藏
页码:300 / 301
页数:3
相关论文
共 9 条
[1]   Cytotoxicity and Induction of Inflammation by Pepsin in Acid in Bronchial Epithelial Cells [J].
Bathoorn, Erik ;
Daly, Paul ;
Gaiser, Birgit ;
Sternad, Karl ;
Poland, Craig ;
MacNee, William ;
Drost, Ellen M. .
INTERNATIONAL JOURNAL OF INFLAMMATION, 2011, 2011
[2]   Airway Pepsin Levels in Otherwise Healthy Surgical Patients Receiving General Anesthesia With Endotracheal Intubation [J].
Bohman, J. Kyle ;
Kor, Daryl J. ;
Kashyap, Rahul ;
Gajic, Ognjen ;
Festic, Emir ;
He, Zhaoping ;
Lee, Augustine S. .
CHEST, 2013, 143 (05) :1407-1413
[3]  
GOLDBERG HI, 1969, GASTROENTEROLOGY, V56, P223
[4]   Acid and Weakly Acidic Gastroesophageal Reflux and Pepsin Isoforms (A and C) in Tracheal Secretions of Critically Ill Children [J].
Hallal, Cristiane ;
Chaves, Veridiana S. ;
Borges, Gilberto C. ;
Werlang, Isabel C. ;
Fontella, Fernanda U. ;
Matte, Ursula ;
Goldani, Marcelo Z. ;
Carvalho, Paulo R. ;
Trotta, Eliana A. ;
Piva, Jefferson P. ;
Barros, Sergio G. S. ;
Goldani, Helena A. S. .
CHEST, 2015, 148 (02) :333-339
[5]   Effect of pepsin on laryngeal stress protein (Sep70, Sep53, and Hsp70) response: Role in laryngopharyngeal reflux disease [J].
Johnston, N ;
Dettmar, PW ;
Lively, MO ;
Postma, GN ;
Belafsky, PC ;
Birchall, M ;
Koufman, JA .
ANNALS OF OTOLOGY RHINOLOGY AND LARYNGOLOGY, 2006, 115 (01) :47-58
[6]   Pepsin and carbonic anhydrase isoenzyme III as diagnostic markers for laryngopharyngeal reflux disease [J].
Johnston, N ;
Knight, J ;
Dettmar, PW ;
Lively, MO ;
Koufman, J .
LARYNGOSCOPE, 2004, 114 (12) :2129-2134
[7]   Activity/stability of human pepsin: Implications for reflux attributed laryngeal disease [J].
Johnston, Nikki ;
Dettmar, Peter W. ;
Bishwokarma, Bimjhana ;
Lively, Mark O. ;
Koufman, Jamie A. .
LARYNGOSCOPE, 2007, 117 (06) :1036-1039
[8]   PH STABILITY AND ACTIVITY CURVES OF PEPSIN WITH SPECIAL REFERENCE TO THEIR CLINICAL IMPORTANCE [J].
PIPER, DW ;
FENTON, BH .
GUT, 1965, 6 (05) :506-&
[9]   Pepsin as a Marker of Extraesophageal Reflux [J].
Samuels, Tina L. ;
Johnston, Nikki .
ANNALS OF OTOLOGY RHINOLOGY AND LARYNGOLOGY, 2010, 119 (03) :203-208