Supramolecular gelatin nanoparticles as matrix metalloproteinase responsive cancer cell imaging probes

被引：58

作者：

Xu, Jun-Hua ^{[1
,2
]}

Gao, Fu-Ping ^{[1
]}

Liu, Xue-Feng ^{[1
]}

Zeng, Qian ^{[1
]}

Guo, Shi-Shang ^{[2
]}

Tang, Zhi-Yong ^{[1
]}

Zhao, Xing-Zhong ^{[2
]}

Wang, Hao ^{[1
]}

机构：

[1] Natl Ctr Nanosci & Technol NCNST, CAS Key Lab Biol Effects Nanomat & Nanosafety, Beijing 100190, Peoples R China

[2] Wuhan Univ, Dept Phys, Sch Phys, Wuhan 430072, Peoples R China

来源：

CHEMICAL COMMUNICATIONS | 2013年 / 49卷 / 40期

基金：

北京市自然科学基金;

关键词：

PHOTOTHERMAL THERAPY; CLINICAL TRANSLATION; DRUG-DELIVERY; DESIGN; AGENTS; GRAPHENE; INTERNALIZATION; FLUORESCENCE; PARTICLES; PATHWAYS;

D O I：

10.1039/c3cc00304c

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

We demonstrate the on-chip preparation of size-controllable supramolecular gelatin nanoparticles (SGNs) with a quantum dot (QD) payload as matrix metalloproteinase (MMP) responsive cancer cell imaging probes.

引用

页码：4462 / 4464

页数：3

共 33 条

[1]

[Anonymous], 2011, BIOMATERIALS APPL NA

[2] Supramolecular Nanodevices: From Design Validation to Theranostic Nanomedicine [J].

Cabral, Horacio ;

Nishiyama, Nobuhiro ;

Kataoka, Kazunori .

ACCOUNTS OF CHEMICAL RESEARCH, 2011, 44 (10) :999-1008

[3] Responsive Theranostic Systems: Integration of Diagnostic Imaging Agents and Responsive Controlled Release Drug Delivery Carriers [J].

Caldorera-Moore, Mary E. ;

Liechty, William B. ;

Peppas, Nicholas A. .

ACCOUNTS OF CHEMICAL RESEARCH, 2011, 44 (10) :1061-1070

[4] Multifunctional Mesoporous Nanoellipsoids for Biological Bimodal Imaging and Magnetically Targeted Delivery of Anticancer Drugs [J].

Chen, Yu ;

Chen, Hangrong ;

Zhang, Shengjian ;

Chen, Feng ;

Zhang, Lingxia ;

Zhang, Jiamin ;

Zhu, Min ;

Wu, Huixia ;

Guo, Limin ;

Feng, Jingwei ;

Shi, Jianlin .

ADVANCED FUNCTIONAL MATERIALS, 2011, 21 (02) :270-278

[5] Ultrahigh Sensitivity Carbon Nanotube Agents for Photoacoustic Molecular Imaging in Living Mice [J].

de la Zerda, Adam ;

Liu, Zhuang ;

Bodapati, Sunil ;

Teed, Robert ;

Vaithilingam, Srikant ;

Khuri-Yakub, Butrus T. ;

Chen, Xiaoyuan ;

Dai, Hongjie ;

Gambhir, Sanjiv Sam .

NANO LETTERS, 2010, 10 (06) :2168-2172

[6]

Deryugina EI, 1998, CANCER RES, V58, P3743

[7] Detecting and Destroying Cancer Cells in More than One Way with Noble Metals and Different Confinement Properties on the Nanoscale [J].

Dreaden, Erik C. ;

El-Sayed, Mostafa A. .

ACCOUNTS OF CHEMICAL RESEARCH, 2012, 45 (11) :1854-1865

[8] New functions for the matrix metalloproteinases in cancer progression [J].

Egeblad, M ;

Werb, Z .

NATURE REVIEWS CANCER, 2002, 2 (03) :161-174

[9] A Highly Emissive Conjugated Polyelectrolyte Vector for Gene Delivery and Transfection [J].

Feng, Xuli ;

Lv, Fengting ;

Liu, Libing ;

Yang, Qiong ;

Wang, Shu ;

Bazan, Guillermo C. .

ADVANCED MATERIALS, 2012, 24 (40) :5428-5432

[10] Multistage Nanovectors: From Concept to Novel Imaging Contrast Agents and Therapeutics [J].

Godin, Biana ;

Tasciotti, Ennio ;

Liu, Xuewu ;

Serda, Rita E. ;

Ferrari, Mauro .

ACCOUNTS OF CHEMICAL RESEARCH, 2011, 44 (10) :979-989

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