A unified theory of gene expression

被引：706

作者：

Orphanides, G

Reinberg, D ^{[1
]}

机构：

[1] Univ Med & Dent New Jersey, Robert Wood Johnson Med Sch, Dept Biochem, Div Nucleic Acids Enzymol,Howard Hughes Med Inst, Piscataway, NJ 08854 USA

[2] Syngenta Cent Toxicol Lab, Macclesfield SK10 4TJ, Cheshire, England

来源：

CELL | 2002年 / 108卷 / 04期

基金：

美国国家卫生研究院;

关键词：

D O I：

10.1016/S0092-8674(02)00655-4

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

The human genome has been called "the blueprint for life." This master plan is realized through the process of gene expression. Recent progress has revealed that many of the steps in the pathway from gene sequence to active protein are connected, suggesting a unified theory of gene expression.

引用

页码：439 / 451

页数：13

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