Mouse models of breast cancer metastasis to bone

被引：26

作者：

Kretschmann, Kelsi L. ^{[1
]}

Welm, Alana L. ^{[1
]}

机构：

[1] Univ Utah, Dept Oncol Sci, Huntsman Canc Inst, Salt Lake City, UT 84112 USA

来源：

CANCER AND METASTASIS REVIEWS | 2012年 / 31卷 / 3-4期

关键词：

Breast cancer; Bone metastasis; Mouse model; TRANSGENIC MICE; MAMMARY-TUMORS; TGF-BETA; HA-RAS; GENES; PROGRESSION; EXPRESSION; INDUCTION; GROWTH;

D O I：

10.1007/s10555-012-9378-4

中图分类号：

R73 [肿瘤学];

学科分类号：

100214 ;

摘要：

Breast cancer frequently metastasizes to bone, where it takes a significant toll on quality of life. Models of bone metastasis are needed in order to better understand the process of bone metastasis and to develop better treatments. Here, we discuss the available mouse models for breast cancer bone metastasis and critical techniques for imaging bone metastasis in these models.

引用

页码：579 / 583

页数：5

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