Colchicine intoxication and infection risk: a case report

被引：12
|
作者：
Kocak, Z. [1 ]
Akay, H. [2 ]
Gucenmez, S. [2 ]
Tufan, A. [3 ]
Donderici, O. [2 ]
机构：
[1] Ankara Res & Training Hosp, Infect Dis & Clin Microbiol Dept, TR-06340 Ankara, Turkey
[2] Ankara Res & Training Hosp, Dept Internal Med, TR-06340 Ankara, Turkey
[3] Ulus Govt Hosp, Dept Internal Med, Ankara, Turkey
来源：
JOURNAL OF CLINICAL PHARMACY AND THERAPEUTICS | 2008年 / 33卷 / 04期
关键词：
colchicine; infection; intoxication; leukocyte dysfunction;
D O I：
10.1111/j.1365-2710.2008.00927.x
中图分类号：
R9 [药学];
学科分类号：
1007 ;
摘要：
Colchicine is widely used, primarily for the treatment of gouty arthritis and familial Mediterranean fever. Colchicine intoxication is a rare but potentially life-threatening event. Herein, we reported a 26-year-old woman who presented to the emergency department after ingesting 27.5 mg of colchicine in a suicide attempt. She exhibited signs typical of colchicine-poisoning and developed infectious complications but with subsequent complete recovery. This paper discusses the role of colchicine poisoning in increasing susceptibility to infections. This aspect is usually under-appreciated in the clinical picture of colchicine overdose.
引用
收藏
页码：451 / 452
页数：2
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