The molecular pathways behind bladder stretch injury

被引：5
作者：
Halachmi, Sarel [1 ,2 ,3 ]
机构：
[1] Technion Israeli Inst Technol, Dept Urol, IL-31096 Haifa, Israel
[2] Technion Israeli Inst Technol, Pediat Urol Serv, Rambam Med Ctr, IL-31096 Haifa, Israel
[3] Technion Israeli Inst Technol, Fac Med, IL-31096 Haifa, Israel
来源：
JOURNAL OF PEDIATRIC UROLOGY | 2009年 / 5卷 / 01期
关键词：
Bladder stretch injury; Molecular pathway; Pathophysiology; Research models;
D O I：
10.1016/j.jpurol.2008.08.003
中图分类号：
R72 [儿科学];
学科分类号：
100202 ;
摘要：
Stretch injury is a non-reversible process that changes the cellular and extracellular characteristics of the bladder wall, leading to bladder dysfunction. Posterior urethral valve and neurogenic bladder are examples of disorders that may lead to stretch injury. There is a lack of understanding of the molecular processes leading to stretch injury. The current literature is reviewed in this paper, with the aim of giving some insight into the molecular and genetic pathways of bladder stretch injury. (C) 2008 Journal of Pediatric Urology Company. Published by Elsevier Ltd. All rights reserved.
引用
收藏
页码：13 / 16
页数：4
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