Dermatologic findings in HIV-1-infected patients: A prospective study with emphasis on CD4+ cell count

被引：27

作者：

ReynaudMendel, B ^{[1
]}

Janier, M ^{[1
]}

Gerbaka, J ^{[1
]}

Hakim, C ^{[1
]}

Rabian, C ^{[1
]}

Chastang, C ^{[1
]}

Morel, P ^{[1
]}

机构：

[1] HOP ST LOUIS,CTR CLIN & BIOL MALAD SEXUELLEMENT TRANSMISSIBLES,F-75010 PARIS,FRANCE

来源：

DERMATOLOGY | 1996年 / 192卷 / 04期

关键词：

skin diseases; prospective study; human immunodeficiency virus; AIDS; CD4+ cell count;

D O I：

10.1159/000246404

中图分类号：

R75 [皮肤病学与性病学];

学科分类号：

100206 ;

摘要：

Background: Skin manifestations are common in patients infected with the human immunodeficiency virus (HIV) but the prognostic significance of many of them is not clear, Methods: Skin disorders were studied in a cohort of 267 HIV-infected patients followed prospectively and were correlated to the CD4+ cell count. Results: Among the most specific to HIV infection, Kaposi's sarcoma, oral hairy leukoplakia, molluscum contagiosum, xerosis and oral candidiasis were statistically associated to a low CD4+ cell count (200-300 CD4+/mm(3); p<0.001). Kaposi's sarcoma, oral candidiasis and molluscum contagiosum were more frequent in homosexual males (p < 0.05). Genital warts were more frequent in intravenous-drug users (p < 0.001). Conclusions: These results suggest that dermatological findings are useful clinical predictors of the presence or progression of HIV infection.

引用

页码：325 / 328

页数：4

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