Ethical issues in longitudinal studies: the case of ELSA-Brasil

被引：22

作者：

Aquino, Estela M. L. ^{[1
]}

Vasconcellos-Silva, Paulo Roberto ^{[2
,3
,4
]}

Coeli, Claudia Medina ^{[5
]}

Araujo, Maria Jenny ^{[1
]}

Santos, Simone M. ^{[6
]}

de Figueiredo, Roberta Carvalho ^{[7
]}

Duncan, Bruce B. ^{[8
]}

机构：

[1] Univ Fed Bahia, Inst Saude Colet, MUSA Programa Integrado Genero & Saude, BR-40110040 Salvador, BA, Brazil

[2] Fundacao Oswaldo Cruz, Inst Oswaldo Cruz, Programa Posgrad Ensino Biociencias & Saude, Rio De Janeiro, RJ, Brazil

[3] Fundacao Oswaldo Cruz, Programa Posgrad Saude Coletiva, Escola Nacl Saude Publ, Rio De Janeiro, RJ, Brazil

[4] Univ Fed Rio de Janeiro, Escola Med & Cirurgia, Dept Med Especializada, Rio De Janeiro, RJ, Brazil

[5] Univ Fed Rio de Janeiro, Inst Estudos Saude Colet, Rio De Janeiro, RJ, Brazil

[6] Fundacao Oswaldo Cruz, Escola Nacl Saude Publ, Rio De Janeiro, RJ, Brazil

[7] Univ Fed Minas Gerais, Fac Med, Programa Posgrad Saude Publ, Belo Horizonte, MG, Brazil

[8] Univ Fed Rio Grande do Sul, Fac Med, Programa Posgrad Epidemiol, Porto Alegre, RS, Brazil

来源：

REVISTA DE SAUDE PUBLICA | 2013年 / 47卷

关键词：

Ethics; Research; Epidemiologic Research Design; Multicenter Studies as Topic; ethics; Cohort Studies; Longitudinal Studies; CONSENT;

D O I：

10.1590/S0034-8910.2013047003804

中图分类号：

R1 [预防医学、卫生学];

学科分类号：

1004 ; 120402 ;

摘要：

The debate about ethics in research with human beings has historically emphasized experimental studies because of their greater potential to harm the subjects involved. However, observational studies also include risks and relevant questions to be discussed. This article aims to present and discuss the ethical aspects involved in the implementation of ELSA-Brasil, a longitudinal multicenter study, with public funding, in which the research subjects and investigators are employees of the same institutions. The procedures adopted to meet the ethical requirements and commitments are described, as well as the casuistics that guided the actions according to their guiding principles (beneficence, autonomy and social justice). We present some moral problems that required consideration of risks and benefits at the confluence with the study's objectives, and we conclude with comments on the peculiarities and the potential benefits of a longitudinal study.

引用

页码：19 / 26

页数：8

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