Silencing of active transposable elements in plants

被引:110
作者
Fultz, Dalen [1 ]
Choudury, Sarah G. [1 ]
Slotkin, R. Keith [1 ,2 ]
机构
[1] Ohio State Univ, Dept Mol Genet, Columbus, OH 43210 USA
[2] Ohio State Univ, Ctr RNA Biol, Columbus, OH 43210 USA
基金
美国国家科学基金会; 美国国家卫生研究院;
关键词
DIRECTED DNA METHYLATION; VEGETATIVE PHASE-CHANGE; RNA-POLYMERASE V; EPIGENETIC INHERITANCE; SIRNA BIOGENESIS; DICER-LIKE; POL-IV; PATHWAY; EXPRESSION; PROTEIN;
D O I
10.1016/j.pbi.2015.05.027
中图分类号
Q94 [植物学];
学科分类号
071001 ;
摘要
In plant genomes the vast majority of transposable elements (TEs) are found in a transcriptionally silenced state that is epigenetically propagated from generation to generation. Although the mechanism of this maintenance of silencing has been well studied, it is now clear that the pathways responsible for maintaining TEs in a silenced state differ from the pathways responsible for initially targeting the TE for silencing. Recently, attention in this field has focused on investigating the molecular mechanisms that initiate and establish TE silencing. Here we review the current models of how TEs are triggered for silencing, the data supporting each model, and the key future questions in this fast moving field.
引用
收藏
页码:67 / 76
页数:10
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