Synthesis and antibacterial activity of some new hydrazones

被引：20
|
作者：
Rudrapal, M. [1 ]
Satyanandam, R. Siva [1 ]
Swaroopini, T. Sri [1 ]
Lakshmi, T. Naga [1 ]
Jaha, S. Kamar [1 ]
Zaheera, S. [1 ]
机构：
[1] Aditya Inst Pharmaceut Sci & Res, Surampalem 533437, Andhra Pradesh, India
来源：
MEDICINAL CHEMISTRY RESEARCH | 2013年 / 22卷 / 06期
关键词：
Hydrazone; Azomethine; Heteroaromatic scaffold; Antibacterial; DERIVATIVES;
D O I：
10.1007/s00044-012-0278-5
中图分类号：
R914 [药物化学];
学科分类号：
100701 ;
摘要：
New hydrazone derivatives were synthesized by the condensation of some selected heteroaromatic hydrazines with appropriate aromatic ketones at high temperature (100 A degrees C). The structures of the synthesized compounds were established by elemental (CHN) and spectral (IR, (HNMR)-H-1, and Mass) analysis. The synthesized compounds were screened for their antibacterial (Bacillus subtilis, Staphylococcus aureus, Escherichia coli, Pseudomonas aeruginosa, Salmonella typhi, Proteus mirabilis) activities, which reveal that all the compounds possess activity against all the tested organisms.
引用
收藏
页码：2840 / 2846
页数：7
相关论文
共 50 条
  • [1] Synthesis and antibacterial activity of some new hydrazones
    M. Rudrapal
    R. Siva Satyanandam
    T. Sri Swaroopini
    T. Naga Lakshmi
    S. Kamar Jaha
    S. Zaheera
    Medicinal Chemistry Research, 2013, 22 : 2840 - 2846
  • [2] ANTIBACTERIAL ACTIVITY OF SOME BENZAZOL HYDRAZONES
    MALYUGA, OA
    CHETVERIKOV, VP
    MAKSIMOV, NY
    PRONINA, TI
    ABAZA, IB
    BEREZINA, TI
    KHIMIKO-FARMATSEVTICHESKII ZHURNAL, 1976, 10 (02): : 60 - 63
  • [3] Synthesis and antibacterial activity of new oximes, semicarbazones and phenyl hydrazones
    Hania, Majed M.
    ASIAN JOURNAL OF CHEMISTRY, 2006, 18 (03) : 1701 - 1704
  • [4] Synthesis and evaluation of some new isatin hydrazones for their antibacterial, antioxidant and cytotoxic activities
    Rao, J. Venkateshwar
    Sarangapani, M.
    ASIAN JOURNAL OF CHEMISTRY, 2008, 20 (07) : 5331 - 5335
  • [5] Synthesis and antibacterial activity of some new azopyrazoles
    Patel, B. P.
    Patel, H. S.
    Shah, P. J.
    BULGARIAN CHEMICAL COMMUNICATIONS, 2010, 42 (04): : 274 - 278
  • [6] SYNTHESIS AND ANTIBACTERIAL ACTIVITY OF SOME NEW MESOIONICS
    PRAKASH, L
    TYAGI, E
    SHAIHLA
    MITAL, RL
    PHARMAZIE, 1991, 46 (04): : 291 - 292
  • [7] Synthesis, Spectral Characterization and Antibacterial activity of Functionalized Hydrazones
    Kasimbi, D.
    Reddy, K. Hussain
    Devanna, N.
    ORIENTAL JOURNAL OF CHEMISTRY, 2019, 35 (02) : 557 - 562
  • [8] Synthesis, antitubercular, antibacterial and antifungal activities of some hydrazones and their spirothiazolidinones
    Alagarsamy, V
    Venkateshperumal, R
    Sathyabhama, S
    Vaishnavapriya, S
    Sakkarapandi, S
    Revathi, S
    Kalaiselvi, R
    Balamurugan, J
    Sevukarajan, M
    INDIAN JOURNAL OF HETEROCYCLIC CHEMISTRY, 2002, 11 (04) : 327 - 328
  • [9] Synthesis and antibacterial activity of some new derivatives of pyrazole
    Mohammad Rahimizadeh
    Mehdi Pordel
    Mehdi Bakavoli
    Shima Rezaeian
    Ali Sadeghian
    World Journal of Microbiology and Biotechnology, 2010, 26 : 317 - 321
  • [10] SYNTHESIS AND ANTIBACTERIAL ACTIVITY OF SOME NEW AMINOPHOSPHINIC ACIDS
    LINFIELD, WM
    JUNGERMANN, E
    GUTTMANN, AT
    JOURNAL OF ORGANIC CHEMISTRY, 1961, 26 (10): : 4088 - &
12345