In Vitro Activities of Nine Antifungal Drugs against 81 Phialophora and Cyphellophora Isolates

被引：20

作者：

Feng, Peiying ^{[3
,6
]}

Najafzadeh, M. Javad ^{[4
,5
,6
]}

Sun, Jiufeng ^{[6
,7
]}

Ahmed, Sarah ^{[6
]}

Xi, Liyan ^{[8
]}

de Hoog, G. Sybren ^{[5
,6
,8
,9
]}

Lai, Wei ^{[3
]}

Lu, Chun ^{[3
]}

Klaassen, Corne H. ^{[2
]}

Meis, Jacques F. ^{[1
,2
]}

机构：

[1] Radboud Univ Nijmegen, Med Ctr, Dept Med Microbiol, NL-6525 ED Nijmegen, Netherlands

[2] Canisius Wilhelmina Hosp, Dept Med Microbiol & Infect Dis, Nijmegen, Netherlands

[3] Sun Yat Sen Univ, Affiliated Hosp 3, Guangzhou 510275, Guangdong, Peoples R China

[4] Mashhad Univ Med Sci, Fac Med, Dept Parasitol & Mycol, Mashhad, Iran

[5] Univ Amsterdam, Inst Biodivers & Ecosyst Dynam, Amsterdam, Netherlands

[6] CBS KNAW Fungal Biodivers Ctr, Utrecht, Netherlands

[7] Sun Yat Sen Univ, Zhongshan Sch Med, Dept Parasitol, Key Lab Trop Dis Control, Guangzhou 510275, Guangdong, Peoples R China

[8] Sun Yat Sen Univ, Sun Yat Sen Mem Hosp, Guangzhou 510275, Guangdong, Peoples R China

[9] Peking Univ, Hlth Sci Ctr, Res Ctr Med Mycol, Beijing 100871, Peoples R China

来源：

ANTIMICROBIAL AGENTS AND CHEMOTHERAPY | 2012年 / 56卷 / 11期

关键词：

FUNGAL; PHEOHYPHOMYCOSIS; ISAVUCONAZOLE; INFECTIONS;

D O I：

10.1128/AAC.01112-12

中图分类号：

Q93 [微生物学];

学科分类号：

071005 ; 100705 ;

摘要：

Cyphellophora guyanensis (n = 15), other Cyphellophora species (n = 11), Phialophora europaea (n = 43), and other Phialophora species (n = 12) were tested in vitro against nine antifungal drugs. The MIC(90)s across all of the strains (n = 81) were, in increasing order, as follows: posaconazole, 0.063 mu g/ml; itraconazole, 0.5 mu g/ml; voriconazole, 1 mu g/ml; micafungin, 1 mu g/ml; terbinafine, 2 mu g/ml; isavuconazole, 4 mu g/ml; caspofungin, 4 mu g/ml; fluconazole, 8 mu g/ml; amphotericin B, 16 mu g/ml.

引用

页码：6044 / 6047

页数：4

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