Exosomes as Messengers between Mother and Fetus in Pregnancy

被引：105

作者：

Czernek, Liliana ^{[1
]}

Duchler, Markus ^{[1
]}

机构：

[1] Polish Acad Sci, Ctr Mol & Macromol Studies, Dept Bioorgan Chem, 112 Sienkiewicza St, PL-90363 Lodz, Poland

来源：

INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES | 2020年 / 21卷 / 12期

关键词：

placenta; exosomes; extracellular vesicles; pregnancy; embryo implantation; PLACENTA-DERIVED EXOSOMES; INTRAUTERINE GROWTH RESTRICTION; HUMAN TROPHOBLAST CELLS; MHC CLASS-I; EXTRACELLULAR VESICLES; 1ST TRIMESTER; MICRORNAS; EMBRYO; PREECLAMPSIA; EXPRESSION;

D O I：

10.3390/ijms21124264

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

The ability of exosomes to transport different molecular cargoes and their ability to influence various physiological factors is already well known. An exciting area of research explores the functions of exosomes in healthy and pathological pregnancies. Placenta-derived exosomes were identified in the maternal circulation during pregnancy and their contribution in the crosstalk between mother and fetus are now starting to become defined. In this review, we will try to summarize actual knowledge about this topic and to answer the question of how important exosomes are for a healthy pregnancy.

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页码：1 / 16

页数：17

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