The use of plasma exchange in Hashimoto's encephalopathy: A case report and review of the literature

被引：30

作者：

Cook, Melissa K. ^{[1
]}

Malkin, Mark ^{[2
]}

Karafin, Matthew S. ^{[3
,4
]}

机构：

[1] Med Coll Wisconsin, Dept Neurol, Milwaukee, WI 53226 USA

[2] Virginia Commonwealth Univ, Dept Neurol, Richmond, VA USA

[3] Blood Ctr Wisconsin, Inst Med Sci, Milwaukee, WI 53201 USA

[4] Med Coll Wisconsin, Dept Pathol, Milwaukee, WI 53226 USA

来源：

JOURNAL OF CLINICAL APHERESIS | 2015年 / 30卷 / 03期

关键词：

Hashimoto's encephalopathy; plasma exchange; pheresis indications; ANTITHYROID ANTIBODIES; DISEASE; THYROIDITIS; PATHOGENESIS;

D O I：

10.1002/jca.21353

中图分类号：

R5 [内科学];

学科分类号：

1002 ; 100201 ;

摘要：

Hashimoto's Encephalopathy (HE) is a very rare condition characterized by psychosis, seizures, cognitive fluctuations, and myoclonus. In a few published cases, plasma exchange has been used due to the theoretical removal of antithyroid peroxidase antibodies (anti-TPO), one of the postulated causes of the condition. We report a case of HE treated by plasma exchange where no clinical or neurophysiologic improvement was observed despite documented reduction of the anti-TPO antibody to levels below the limits of laboratory detection. We discuss these findings in the context of the known literature for this disease process. J. Clin. Apheresis 30:188-192, 2015. (c) 2014 Wiley Periodicals, Inc.

引用

页码：188 / 192

页数：5

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