Heterologous expression of a position 2-substituted (1→3)-β-D-glucan in Lactococcus lactis

被引:22
|
作者
Werning, Maria Laura y [1 ]
Corrales, Maria Angeles [1 ]
Prieto, Alicia [1 ]
de Palencia, Pilar Fernandez [1 ]
Navas, Jesus [2 ]
Lopez, Paloma [1 ]
机构
[1] CSIC, Ctr Invest Biol, Dept Ciencia Prot, E-28040 Madrid, Spain
[2] Univ Cantabria, Fac Med, CSIC,Ctr Invest Biol, Unidad Asoc,Dept Biol Mol, Santander 39011, Spain
关键词
D O I
10.1128/AEM.00463-08
中图分类号
Q81 [生物工程学(生物技术)]; Q93 [微生物学];
学科分类号
071005 ; 0836 ; 090102 ; 100705 ;
摘要
Exopolysaccharides play an important role in the rheology and texture of fermented foods, and among these beta-glucaus have immunomodulating properties. We show that the overproduction of the Pediococcus parvulus GTF glycosyltransferase in an uncapsulated Lactococcus lactis strain results in synthesis and secretion (300 mg liter(-1)) of a position 2-substituted (1 -> 3)-beta-D-glucan that has potential use as a food additive.
引用
收藏
页码:5259 / 5262
页数:4
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