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Heterologous expression of a position 2-substituted (1→3)-β-D-glucan in Lactococcus lactis
被引:22
|作者:
Werning, Maria Laura y
[1
]
Corrales, Maria Angeles
[1
]
Prieto, Alicia
[1
]
de Palencia, Pilar Fernandez
[1
]
Navas, Jesus
[2
]
Lopez, Paloma
[1
]
机构:
[1] CSIC, Ctr Invest Biol, Dept Ciencia Prot, E-28040 Madrid, Spain
[2] Univ Cantabria, Fac Med, CSIC,Ctr Invest Biol, Unidad Asoc,Dept Biol Mol, Santander 39011, Spain
关键词:
D O I:
10.1128/AEM.00463-08
中图分类号:
Q81 [生物工程学(生物技术)];
Q93 [微生物学];
学科分类号:
071005 ;
0836 ;
090102 ;
100705 ;
摘要:
Exopolysaccharides play an important role in the rheology and texture of fermented foods, and among these beta-glucaus have immunomodulating properties. We show that the overproduction of the Pediococcus parvulus GTF glycosyltransferase in an uncapsulated Lactococcus lactis strain results in synthesis and secretion (300 mg liter(-1)) of a position 2-substituted (1 -> 3)-beta-D-glucan that has potential use as a food additive.
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页码:5259 / 5262
页数:4
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