Synthesis of 2-Aryl-5-oxo-4-[2-(phenylmethylidene)hydrazino]-2,5-dihydro-1H-pyrrole-3-carboxylates by the Reaction between Hydrazones, Acetylenedicarboxylates, and 1-Aryl-N,N′-bis(arylmethylidene)methanediamines

被引：1

作者：

Alizadeh, Abdolali ^{[1
]}

Saberi, Vahid ^{[1
]}

Mokhtari, Javad ^{[1
]}

机构：

[1] Tarbiat Modares Univ, Dept Chem, Tehran, Iran

来源：

HELVETICA CHIMICA ACTA | 2013年 / 96卷 / 10期

关键词：

Hydrazine hydrate; Aldehydes; Acetylenedicarboxylates; dialkyl; Methanediamine; 1-aryl-N; N-bis(arylmethylidene)-; Multicomponent reactions;

D O I：

10.1002/hlca.201300116

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

An efficient approach for the preparation of functionalized 2-aryl-2,5-dihydro-5-oxo-4-[2-(phenylmethylidene)hydrazino]-1H-pyrroles is described. The four-component reaction between aldehydes, NH2NH2H2O, dialkyl acetylenedicarboxylates, and 1-aryl-N,N-bis(arylmethylidene)methanediamines proceeds in EtOH under reflux in good-to-excellent yields (Scheme1). The structures of 4 were corroborated spectroscopically (IR, H-1- and C-13-NMR, and EI-MS, and, in the case of 4f, by X-ray crystallography). A plausible mechanism for this type of reaction is proposed (Scheme2).

引用

页码：1991 / 1996

页数：6

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