Why is Pseudomonas aeruginosa a common cause of infection in individuals with cystic fibrosis?

被引:0
作者
Gross, Jeremy [1 ]
Welch, Martin [1 ]
机构
[1] Univ Cambridge, Dept Biochem, Cambridge CB2 1QW, England
基金
英国生物技术与生命科学研究理事会;
关键词
antibiotic resistance; cystic fibrosis; microbial adaptation; Pseudomonas aeruginosa; BIOFILMS;
D O I
10.2217/FMB.13.40
中图分类号
Q93 [微生物学];
学科分类号
071005 ; 100705 ;
摘要
引用
收藏
页码:697 / 699
页数:3
相关论文
共 19 条
[1]   Adult cystic fibrosis exacerbations and new strains of Pseudomonas aeruginosa [J].
Aaron, SD ;
Ramotar, K ;
Ferris, W ;
Vandemheen, K ;
Saginur, R ;
Tullis, E ;
Haase, D ;
Kottachchi, D ;
St Denis, M ;
Chan, F .
AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE, 2004, 169 (07) :811-815
[2]   Antibiotic pressure compensates the biological cost associated with Pseudomonas aeruginosa hypermutable phenotypes in vitro and in a murine model of chronic airways infection [J].
Alcala-Franco, Beatriz ;
Montanari, Sara ;
Cigana, Cristina ;
Bertoni, Giovanni ;
Oliver, Antonio ;
Bragonzi, Alessandra .
JOURNAL OF ANTIMICROBIAL CHEMOTHERAPY, 2012, 67 (04) :962-969
[3]   Pseudomonas aeruginosa recognizes and responds aggressively to the presence of polymorphonuclear leukocytes [J].
Alhede, Morten ;
Bjarnsholt, Thomas ;
Jensen, Peter O. ;
Phipps, Richard Kerry ;
Moser, Claus ;
Christophersen, Lars ;
Christensen, Louise Dahl ;
van Gennip, Maria ;
Parsek, Matt ;
Hoiby, Niels ;
Rasmussen, Thomas Bovbjerg ;
Givskov, Michael .
MICROBIOLOGY-SGM, 2009, 155 :3500-3508
[4]   Pseudomonas aeruginosa Evasion of Phagocytosis Is Mediated by Loss of Swimming Motility and Is Independent of Flagellum Expression [J].
Amiel, Eyal ;
Lovewell, Rustin R. ;
O'Toole, George A. ;
Hogan, Deborah A. ;
Berwin, Brent .
INFECTION AND IMMUNITY, 2010, 78 (07) :2937-2945
[5]   Pseudomonas aeruginosa Biofilms in the Respiratory Tract of Cystic Fibrosis Patients [J].
Bjarnsholt, Thomas ;
Jensen, Peter Ostrup ;
Fiandaca, Mark J. ;
Pedersen, Jette ;
Hansen, Christine Ronne ;
Andersen, Claus Bogelund ;
Pressler, Tacjana ;
Givskov, Michael ;
Hoiby, Niels .
PEDIATRIC PULMONOLOGY, 2009, 44 (06) :547-558
[6]   Evidence for airway surface dehydration as the initiating event in CF airway disease [J].
Boucher, R. C. .
JOURNAL OF INTERNAL MEDICINE, 2007, 261 (01) :5-16
[7]   Airway epithelial control of Pseudomonas aeruginosa infection in cystic fibrosis [J].
Carnpodonico, Victoria L. ;
Gadjeva, Mihaela ;
Paradis-Bleau, Catherine ;
Uluer, Ahmet ;
Pier, Gerald B. .
TRENDS IN MOLECULAR MEDICINE, 2008, 14 (03) :120-133
[8]  
Cox MB, 2010, PLOS ONE, V5, DOI [10.1371/journal.pone.0012132, 10.1371/journal.pone.0011044]
[9]   Molecular Epidemiology of Chronic Pseudomonas aeruginosa Airway Infections in Cystic Fibrosis [J].
Cramer, Nina ;
Wiehlmann, Lutz ;
Ciofu, Oana ;
Tamm, Stephanie ;
Hoiby, Niels ;
Tuemmler, Burkhard .
PLOS ONE, 2012, 7 (11)
[10]   Active Starvation Responses Mediate Antibiotic Tolerance in Biofilms and Nutrient-Limited Bacteria [J].
Dao Nguyen ;
Joshi-Datar, Amruta ;
Lepine, Francois ;
Bauerle, Elizabeth ;
Olakanmi, Oyebode ;
Beer, Karlyn ;
McKay, Geoffrey ;
Siehnel, Richard ;
Schafhauser, James ;
Wang, Yun ;
Britigan, Bradley E. ;
Singh, Pradeep K. .
SCIENCE, 2011, 334 (6058) :982-986