Approaches to functional genomics in filamentous fungi

被引：137
作者：
Weld, RJ
Plummer, KM
Carpenter, MA
Ridgway, HJ
机构：
[1] Lincoln Univ, Natl Ctr Adv Bioprotect Technol, Canterbury, New Zealand
[2] La Trobe Univ, Melbourne, Vic 3086, Australia
来源：
CELL RESEARCH | 2006年 / 16卷 / 01期
关键词：
functional genomics; gene replacement; filamentous fungi; homologous recombination; RNAi; gene silencing; oomycetes;
D O I：
10.1038/sj.cr.7310006
中图分类号：
Q2 [细胞生物学];
学科分类号：
071009 ; 090102 ;
摘要：
The study of gene function in filamentous fungi is a field of research that has made great advances in very recent years. A number of transformation and gene manipulation strategies have been developed and applied to a diverse and rapidly expanding list of economically important filamentous fungi and oomycetes. With the significant number of fungal genomes now sequenced or being sequenced, functional genomics promises to uncover a. great deal of new information in coming years. This review discusses recent advances that have been made in examining gene function in filamentous fungi and describes the advantages and limitations of the different approaches.
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收藏
页码：31 / 44
页数：14
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