Dementia and neuroimaging

被引：10

作者：

Agosta, Federica ^{[1
]}

Caso, Francesca ^{[1
]}

Filippi, Massimo ^{[1
,2
]}

机构：

[1] Univ Vita Salute San Raffaele, Neuroimaging Res Unit, San Raffaele Sci Inst, Div Neurosci,Inst Expt Neurol, I-20132 Milan, Italy

[2] Univ Vita Salute San Raffaele, Dept Neurol, San Raffaele Sci Inst, I-20132 Milan, Italy

来源：

JOURNAL OF NEUROLOGY | 2013年 / 260卷 / 02期

关键词：

Dementia; Magnetic resonance imaging; Diffusion tensor MRI; Functional MRI; Positron emission tomography; CREUTZFELDT-JAKOB-DISEASE; FRONTOTEMPORAL LOBAR DEGENERATION; HEXANUCLEOTIDE REPEAT EXPANSION; AMYOTROPHIC-LATERAL-SCLEROSIS; WHITE-MATTER; ALZHEIMERS-DISEASE; COGNITIVE IMPAIRMENT; LADIS LEUKOARAIOSIS; HIPPOCAMPAL ATROPHY; PARKINSONS-DISEASE;

D O I：

10.1007/s00415-012-6778-x

中图分类号：

R74 [神经病学与精神病学];

学科分类号：

摘要：

Early diagnosis of dementing conditions and an accurate monitoring of their progression are important clinical and research goals, especially given the improving prospects of disease-modifying therapies. Neuroimaging has played and is playing an important role in detecting reversible, treatable causes of dementia, and in characterizing the dementia syndromes by demonstrating structural and functional signatures that can aid in their differentiation. Many new imaging techniques and modalities are also available that allow the assessment of specific aspects of brain structure and function, such as positron emission tomography with new ligands, diffusion tensor magnetic resonance imaging (MRI) and functional MRI. In this review, we report the most recent findings from the papers published in the Journal of Neurology that used conventional and advanced neuroimaging techniques for the study of various dementing conditions.

引用

页码：685 / 691

页数：7

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