The chemical composition of lithogenic components in Pliocene sediments from the eastern Mediterranean displays periodic variations that are related to earths orbital parameters owing to changes in insolation of the northern hemisphere. This can be explained by two different paleoclimatic/palaeoceanographic scenarios. During oligotrophic periods. similar to those persisting in the modern Mediterranean, sedimentation is rather uniform, and sediments receive high proportions of eolian material from the surrounding deserts. During more humid intervals sedimentation is dominated by fluviatile material that has been introduced by the Nile and northern borderland rivers. Higher nutrient loads associated with enhanced riverine input and a change in water circulation led to eutrophication, water column anoxia, and sapropel deposition in the eastern Mediterranean. Our investigations confirm earlier works claiming that in large parts of the northern Sahara palaeoclimatic conditions changed frequently from arid to more humid. Our results suggest that these changes in the Pliocene match with the approximately 22-ka insolation cyclicity.