Clinical significance of examining IL-2R in peripheral blood lymphocytes of patients with gastric cancer

被引：0
|
作者：
Wang, XH [1 ]
Xu, SH
Lü, GQ
Feng, JG
Zhou, XM
Zhu, CH
机构：
[1] Zhejiang Canc Res Inst, Hangzhou 310022, Peoples R China
[2] Zhejiang Canc Hosp, Dept Thorac Surg, Hangzhou 310022, Peoples R China
来源：
CHINESE MEDICAL JOURNAL | 2001年 / 114卷 / 12期
关键词：
interleukin-2; receptor; flow cytometry; cancer; gastric; lymphocyte;
D O I：
暂无
中图分类号：
R5 [内科学];
学科分类号：
1002 ; 100201 ;
摘要：
Objective To understand the clinical significance of membrane receptors of interleukin-2 ( CD25) in peripheral blood lymphocytes (PBL) of patients with gastric cancer, Methods CD25 percentages in PBL from 110 patients with gastric cancer and 100 normal individuals were examined by flow cytometry. Results were analyzed clinically and pathologically. Results Mean CD25% in PBL from normal individuals and patients with gastric cancer were 17.24 +/- 5.33 and 22.47 +/- 6.82, respectively, and the difference was significant (P < 0.01). Abnormally elevated CD25% in PBL from patients with gastric cancer were correlated with tumor site, macropathology type, tumor size, differentiation degree and clinical stage. Conclusion Measuring CD25% in PBL from gastric cancer patients before surgery may provide a reference for diagnosis, immune treatment and judging prognosis.
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页码：1320 / 1322
页数：3
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