Chemical synthesis of a skeleton structure of sperm CD52 - A GPI-anchored glycopeptide

被引：49

作者：

Shao, N ^{[1
]}

Xue, B ^{[1
]}

Guo, ZW ^{[1
]}

机构：

[1] Case Western Reserve Univ, Dept Chem, Cleveland, OH 44106 USA

来源：

ANGEWANDTE CHEMIE-INTERNATIONAL EDITION | 2004年 / 43卷 / 12期

关键词：

antigens; carbohydrates; glycopepticles; glycoproteins; solid-phase synthesis;

D O I：

10.1002/anie.200353251

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

Going native: A highly convergent synthetic strategy was established to prepare a skeleton structure of sperm CD52 antigen (depicted), which represents the first chemical synthesis of a complex, all natively linked glycosylphosphatidylinositol (GPI)-glycopeptide conjugate.

引用

页码：1569 / 1573

页数：5

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