I2-TBHP-catalyzed one-pot highly efficient synthesis of 4,3-fused 1,2,4-triazoles from N-tosylhydrazones and aromatic N-heterocycles via intermolecular formal 1,3-dipolar cycloaddition

被引：41

作者：

Inturi, Surendra Babu ^{[1
,2
]}

Kalita, Biswajit ^{[1
]}

Ahamed, A. Jafar ^{[2
]}

机构：

[1] Jubilant Biosys Ltd, Div Med Chem, 96 Ind Suburb,2nd Stage, Bangalore 560022, Karnataka, India

[2] Bharathidasan Univ, Jamal Mohamed Coll Autonomous, Postgrad & Res Dept Chem, Tiruchirappalli 620020, Tamil Nadu, India

来源：

ORGANIC & BIOMOLECULAR CHEMISTRY | 2016年 / 14卷 / 47期

关键词：

IODINE-MEDIATED SYNTHESIS; MOLECULAR-IODINE; METAL-FREE; INTRAMOLECULAR CYCLIZATION; OXIDATIVE AMINATION; C(SP(3))-H BONDS; HYDRAZONES; DERIVATIVES; 2-HYDRAZINOPYRIDINE; TRIAZOLOPYRIDINES;

D O I：

10.1039/c6ob01926a

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

I-2-TBHP-catalyzed azomethine imine generation and subsequent regioselective 1,3-dipolar cycloaddition (DC) with aromatic N-heterocycles was developed to afford various 4,3-fused 1,2,4-triazoles in excellent yields. The method is operationally simple and highly efficient with broad functional group tolerance.

引用

页码：11061 / 11064

页数：4

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