MMP-12 Modulation of Intestinal Epithelial Tight Junction Barrier Is Mediated by P38 Kinase Activation of Myosin Light Chain Kianse (MLCK)

被引:0
作者
Al-Sadi, Rana
Nighot, Prashant K.
Ma, Thomas Y.
机构
关键词
D O I
暂无
中图分类号
R57 [消化系及腹部疾病];
学科分类号
摘要
Su1902
引用
收藏
页码:S548 / S548
页数:1
相关论文
共 44 条
[31]   Intestinal damage and myosin light chain kinase (MLCK)-dependent epithelial barrier dysfunction drive minor mismatch graft-versus-host disease (GVHD) [J].
Nalle, Sam ;
Savage, Peter ;
Turner, Jerrold .
FASEB JOURNAL, 2011, 25
[32]   PROTON PUMP INHIBITORS (PPI) INDUCES INCREASE IN GASTRIC EPITHELIAL TIGHT JUNCTION PERMEABILITY VIA ACTIVATION OF MYOSIN LIGHT-CHAIN KINASE [J].
Nighot, Meghali P. ;
Mccarthy, Denis M. ;
Ma, Thomas Y. .
GASTROENTEROLOGY, 2017, 152 (05) :S888-S888
[33]   Matrix Metalloproteinase-9 (MMP-9) induced disruption of intestinal epithelial tight junction barrier is mediated by NF-κB activation [J].
Al-Sadi, Rana ;
Engers, Jessica ;
Haque, Mohammad ;
King, Steven ;
Al-Omari, Deemah ;
Ma, Thomas Y. .
PLOS ONE, 2021, 16 (04)
[34]   Berberine Ameliorates Intestinal Epithelial Tight-Junction Damage and Down-regulates Myosin Light Chain Kinase Pathways in a Mouse Model of Endotoxinemia [J].
Gu, Lili ;
Li, Ning ;
Gong, Jianfeng ;
Li, Qiurong ;
Zhu, Weiming ;
Li, Jieshou .
JOURNAL OF INFECTIOUS DISEASES, 2011, 203 (11) :1602-1612
[35]   Mechanism of Lipopolysaccharides-Induced Increase in Intestinal Epithelial Tight Junction Permeability in-Vitro and In-Vivo: Role of Myosin Light Chain Kinase [J].
Guo, Shuhong ;
Al-Sadi, Rana ;
Ye, Dongmei ;
Ma, Thomas Y. .
GASTROENTEROLOGY, 2012, 142 (05) :S808-S808
[36]   OTA induces intestinal epithelial barrier dysfunction and tight junction disruption in IPEC-J2 cells through ROS/Ca2+-mediated MLCK activation [J].
Wang, Hong ;
Zhai, Nianhui ;
Chen, Ying ;
Fu, Chongyang ;
Huang, Kehe .
ENVIRONMENTAL POLLUTION, 2018, 242 :106-112
[37]   Phosphatidylinositol 3-kinase controls human intestinal epithelial cell differentiation by promoting adherens junction assembly and p38 MAPK activation [J].
Laprise, P ;
Chailler, P ;
Houde, M ;
Beaulieu, JF ;
Boucher, MJ ;
Rivard, N .
JOURNAL OF BIOLOGICAL CHEMISTRY, 2002, 277 (10) :8226-8234
[38]   Intracellular Calcium and Myosin Light Chain Kinase (MLCK) Activation are Involved in the Mechanism of Dextran Sodium Sulfate (DSS)-Induced Tight Junction (TJ) Disruption in CACO-2 Cell Monolayers [J].
Samak, Geetha ;
Turner, Jerrold R. ;
Rao, Radhakrishna .
GASTROENTEROLOGY, 2010, 138 (05) :S272-S272
[39]   Carbachol ameliorates lipopolysaccharide-induced intestinal epithelial tight junction damage by down-regulating NF-κβ and myosin light-chain kinase pathways [J].
Zhang, Ying ;
Li, Jianguo .
BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS, 2012, 428 (02) :321-326
[40]   Up-regulation of Tight-Junction Proteins by p38 Mitogen-Activated Protein Kinase/p53 Inhibition Leads to a Reduction of Injury to the Intestinal Mucosal Barrier in Severe Acute Pancreatitis [J].
Ouyang, Jun ;
Zhang, Zhao-hui ;
Zhou, Yue-xian ;
Niu, Wan-cheng ;
Zhou, Feng ;
Shen, Chang-bing ;
Chen, Ren-guo ;
Li, Xi .
PANCREAS, 2016, 45 (08) :1136-1144