Noise-based tube current reduction method with iterative reconstruction for reduction of radiation exposure in coronary CT angiography

被引：17

作者：

Shen, Junlin ^{[1
]}

Du, Xiangying ^{[1
]}

Guo, Daode ^{[1
]}

Cao, Lizhen ^{[1
]}

Gao, Yan ^{[1
]}

Bai, Mei ^{[2
]}

Li, Pengyu ^{[1
]}

Liu, Jiabin ^{[1
]}

Li, Kuncheng ^{[1
]}

机构：

[1] Capital Med Univ, Xuanwu Hosp, Dept Radiol, Beijing 100053, Peoples R China

[2] Capital Med Univ, Xuanwu Hosp, Dept Biomed Engn, Beijing 100053, Peoples R China

来源：

EUROPEAN JOURNAL OF RADIOLOGY | 2013年 / 82卷 / 02期

关键词：

Iterative reconstruction; Coronary CT angiography; Radiation dose; IMAGE QUALITY; PROTOCOL;

D O I：

10.1016/j.ejrad.2012.10.008

中图分类号：

R8 [特种医学]; R445 [影像诊断学];

学科分类号：

1002 ; 100207 ; 1009 ;

摘要：

Purpose: To investigate the potential of noise-based tube current reduction method with iterative reconstruction to reduce radiation exposure while achieving consistent image quality in coronary CT angiography (CCTA). Materials and methods: 294 patients underwent CCTA on a 64-detector row CT equipped with iterative reconstruction. 102 patients with fixed tube current were assigned to Group 1, which was used to establish noise-based tube current modulation formulas, where tube current was modulated by the noise of test bolus image. 192 patients with noise-based tube current were randomly assigned to Group 2 and Group 3. Filtered back projection was applied for Group 2 and iterative reconstruction for Group 3. Qualitative image quality was assessed with a 5 point score. Image noise, signal intensity, volume CT dose index, and dose-length product were measured. Results: The noise-based tube current modulation formulas were established through regression analysis using image noise measurements in Group 1. Image noise was precisely maintained at the target value of 35.00 HU with small interquartile ranges for Group 2 (34.17-35.08 HU) and Group 3 (34.34-35.03 HU), while it was from 28.41 to 36.49 HU for Group 1. All images in the three groups were acceptable for diagnosis. A relative 14% and 41% reduction in effective dose for Group 2 and Group 3 were observed compared with Group 1. Conclusion: Adequate image quality could be maintained at a desired and consistent noise level with overall 14% dose reduction using noise-based tube current reduction method. The use of iterative reconstruction further achieved approximately 40% reduction in effective dose. (c) 2012 Elsevier Ireland Ltd. All rights reserved.

引用

页码：349 / 355

页数：7