Synthesis, characterization and antimicrobial activity of thiazole, benzothiazole and pyrimidine derivatives bearing sydnone moieties

被引：18

作者：

Asundaria, S. T. ^{[1
]}

Patel, K. C. ^{[1
]}

机构：

[1] Veer Narmad S Gujarat Univ, Dept Chem, Surat 395007, India

来源：

PHARMACEUTICAL CHEMISTRY JOURNAL | 2012年 / 45卷 / 12期

关键词：

Sydnone; thiazole; benzothiazole; pyrimidine; sulfonamide; antimicrobial activity; BIOLOGICAL EVALUATION; INHIBITORS;

D O I：

10.1007/s11094-012-0712-5

中图分类号：

R914 [药物化学];

学科分类号：

100701 ;

摘要：

The synthesis of sydnone sulfonamides bearing thiazole, benzothiazole and pyrimidine heterocycles is described. The newly synthesized compounds were characterized by IR, NMR and elemental analysis and evaluated for their antibacterial activity against some important Gram-positive and Gram-negative bacterial strains. Most of these compounds showed good to moderate activity against tested microbes.

引用

页码：725 / 731

页数：7

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