Working Hard or Hardly Working? Regulatory Bottlenecks in Developing a COVID-19 Vaccine

被引：11
作者：
Pregelj, Lisette [1 ,2 ]
Hine, Damian C. [3 ]
Oyola-Lozada, Maria G. [1 ,4 ]
Munro, Trent P. [5 ]
机构：
[1] Univ Queensland, Sch Chem & Mol Biosci, St Lucia, Qld 4072, Australia
[2] Univ Queensland, Australian Inst Business & Econ, St Lucia, Qld 4072, Australia
[3] Univ Limerick, Kemmy Business Sch, Limerick V94 T9PX, Ireland
[4] Univ Queensland, Fac Business Econ & Law, St Lucia, Qld 4072, Australia
[5] Univ Queensland, Australian Inst Bioengn & Nanotechnol, St Lucia, Qld 4072, Australia
来源：
TRENDS IN BIOTECHNOLOGY | 2020年 / 38卷 / 09期
关键词：
EPIDEMIC;
D O I：
10.1016/j.tibtech.2020.06.004
中图分类号：
Q81 [生物工程学（生物技术）]; Q93 [微生物学];
学科分类号：
071005 ; 0836 ; 090102 ; 100705 ;
摘要：
Vaccine solutions rarely reach the public until after an outbreak abates; an Ebola vaccine was approved 5 years after peak outbreak and SARS, MERS, and Zika vaccines are still in clinical development. Despite massive leaps forward in rapid science, other regulatory bottlenecks are hamstringing the global effort for pandemic vaccines.
引用
收藏
页码：943 / 947
页数：5
相关论文
共 14 条
  • [1] Akanmori B, 2015, WHO DRUG INFORM, V29, P127
  • [2] A new twenty-first century science for effective epidemic response
    Bedford, Juliet
    Farrar, Jeremy
    Ihekweazu, Chikwe
    Kang, Gagandeep
    Koopmans, Marion
    Nkengasong, John
    [J]. NATURE, 2019, 575 (7781) : 130 - 136
  • [3] Molecular Diagnosis of a Novel Coronavirus (2019-nCoV) Causing an Outbreak of Pneumonia
    Chu, Daniel K. W.
    Pan, Yang
    Cheng, Samuel M. S.
    Hui, Kenrie P. Y.
    Krishnan, Pavithra
    Liu, Yingzhi
    Ng, Daisy Y. M.
    Wan, Carrie K. C.
    Yang, Peng
    Wang, Quanyi
    Peiris, Malik
    Poon, Leo L. M.
    [J]. CLINICAL CHEMISTRY, 2020, 66 (04) : 549 - 555
  • [4] Corman VM, 2012, EUROSURVEILLANCE, V17, P3
  • [5] FDA Approval and Regulation of Pharmaceuticals, 1983-2018
    Darrow, Jonathan J.
    Avorn, Jerry
    Kesselheim, Aaron S.
    [J]. JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION, 2020, 323 (02): : 164 - 176
  • [6] Davis J.S, 2020, MED J AUST
  • [7] An interactive web-based dashboard to track COVID-19 in real time
    Dong, Ensheng
    Du, Hongru
    Gardner, Lauren
    [J]. LANCET INFECTIOUS DISEASES, 2020, 20 (05) : 533 - 534
  • [8] On a path to accelerate access to Ebola vaccines: The WHO's research and development efforts during the 2014-2016 Ebola epidemic in West Africa
    Henao-Restrepo, Ana Maria
    Preziosi, Marie-Pierre
    Wood, David
    Moorthy, Vasee
    Kieny, Marie Paule
    [J]. CURRENT OPINION IN VIROLOGY, 2016, 17 : 138 - 144
  • [9] The pandemic pipeline
    Hodgson, John
    [J]. NATURE BIOTECHNOLOGY, 2020, 38 (05) : 523 - 532
  • [10] Kupferschmidt K., 2020, SCIENCE, DOI DOI 10.1126/SCIENCE.ABB4761
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