HIV Infection and Osteoporosis: Pathophysiology, Diagnosis, and Treatment Options

被引：22

作者：

Rothman, Micol S. ^{[1
]}

Bessesen, Mary T. ^{[2
,3
]}

机构：

[1] Univ Colorado Sch Med, Dept Med Endocrinol Diabet & Metab, Aurora, CO 80045 USA

[2] Eastern Colorado Healthcare Syst, Dept Vet Affairs, Denver, CO 80220 USA

[3] Univ Colorado Sch Med, Div Infect Dis, Dept Med, Aurora, CO 80045 USA

来源：

CURRENT OSTEOPOROSIS REPORTS | 2012年 / 10卷 / 04期

关键词：

HIV infection; Osteoporosis; Bone density; Fracture; HAART; BONE-MINERAL DENSITY; ANTIRETROVIRAL THERAPY; PROTEASE INHIBITORS; ABACAVIR-LAMIVUDINE; RISK-FACTORS; VITAMIN-D; T-CELLS; ZOLEDRONATE; PREVALENCE; INITIATION;

D O I：

10.1007/s11914-012-0125-0

中图分类号：

R5 [内科学];

学科分类号：

1002 ; 100201 ;

摘要：

As the population with HIV continues to age, specialists in HIV care are increasingly encountering chronic health conditions, which now include osteoporosis, osteopenia, and fragility fractures. The pathophysiology of the bone effects of HIV infection is complex and includes traditional risk factors for bone loss as well as specific effects due to the virus itself, chronic inflammation, and HAART. Examining risk factors for low bone density and screening of certain patients is suggested, and consideration should be given to treatment for those considered high risk for fracture.

引用

页码：270 / 277

页数：8

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