Hepatitis C transmission - where are we now?

被引:29
作者
Clarke, A [1 ]
Kulasegaram, R [1 ]
机构
[1] St Thomas Hosp, NHS Trust, London SE1 7EH, England
关键词
hepatitis C; transmission; sexual; HIV;
D O I
10.1258/095646206775455685
中图分类号
R392 [医学免疫学]; Q939.91 [免疫学];
学科分类号
100102 ;
摘要
Since the discovery of hepatitis C virus (HCV) in 1989, there has been much debate regarding its potential modes of transmission particularly as only about half of the reported cases of acute HCV have a defined parenteral exposure. It has been clearly established that blood-blood contact is important in its transmission, but the question of sexual transmission has caused more controversy with studies producing conflicting evidence. The objective of this review was to examine the current evidence on all reported routes of transmission of hepatitis C with particular attention to sexual transmission in men having sex with men (MSM) and HIV-positive individuals. We conducted PubMed searches using keywords hepatitis C, transmission, sexual, HIV, MSM, mother to child, haemophilia, intravenous drug use, tattooing and skin piercing. The bibliographies in articles identified were also searched.
引用
收藏
页码:74 / 80
页数:7
相关论文
共 90 条
[51]   Transmission of hepatitis C virus: Rates, routes, and cofactors [J].
MacDonald, M ;
Crofts, N ;
Kaldor, J .
EPIDEMIOLOGIC REVIEWS, 1996, 18 (02) :137-148
[52]   Role of beauty treatment in the spread of parenterally transmitted hepatitis viruses in Italy [J].
Mariano, A ;
Mele, A ;
Tosti, ME ;
Parlato, A ;
Gallo, G ;
Ragni, P ;
Zotti, C ;
Lopalco, P ;
Pompa, MG ;
Graziani, G ;
Stroffolini, T .
JOURNAL OF MEDICAL VIROLOGY, 2004, 74 (02) :216-220
[53]   Absence of hepatitis C virus transmission in a prospective cohort of heterosexual serodiscordant couples [J].
Marincovich, B ;
Castilla, J ;
del Romero, J ;
García, S ;
Hernando, V ;
Raposo, M ;
Rodríguez, C .
SEXUALLY TRANSMITTED INFECTIONS, 2003, 79 (02) :160-162
[54]   Association of hepatitis C virus infection with sexual exposure in southern India [J].
Marx, MA ;
Murugavel, KG ;
Tarwater, PM ;
SriKrishnan, AK ;
Thomas, DL ;
Solomon, S ;
Celentano, DD .
CLINICAL INFECTIOUS DISEASES, 2003, 37 (04) :514-520
[55]   Comparison of hepatitis C viral loads in patients with or without human immunodeficiency virus [J].
Matthews-Greer, JM ;
Caldito, GC ;
Adley, SD ;
Willis, R ;
Mire, AC ;
Jamison, RM ;
McRae, KL ;
King, JW ;
Chang, WL .
CLINICAL AND DIAGNOSTIC LABORATORY IMMUNOLOGY, 2001, 8 (04) :690-694
[56]   TRANSMISSION OF HEPATITIS-C VIRUS TO CHILDREN AND HUSBANDS BY WOMEN INFECTED WITH CONTAMINATED ANTI-D IMMUNOGLOBULIN [J].
MEISEL, H ;
REIP, A ;
FALTUS, B ;
LU, MJ ;
PORST, H ;
WIESE, M ;
ROGGENDORF, M ;
KRUGER, DH .
LANCET, 1995, 345 (8959) :1209-1211
[57]   SEXUAL TRANSMISSION OF HEPATITIS-C VIRUS - COHORT STUDY (1981-9) AMONG EUROPEAN HOMOSEXUAL MEN [J].
MELBYE, M ;
BIGGAR, RJ ;
WANTZIN, P ;
KROGSGAARD, K ;
EBBESEN, P ;
BECKER, NG .
BRITISH MEDICAL JOURNAL, 1990, 301 (6745) :210-212
[58]   Significance of sexual route of transmission of hepatitis B and C in Russia [J].
Mikhailov, MI ;
Gomberg, MA ;
Dolzhanskaya, NA ;
Koubanova, AA .
INTERNATIONAL JOURNAL OF STD & AIDS, 2002, 13 :9-11
[59]  
Montella M, 2004, GUT, V53, P771
[60]  
Pando MDP, 2004, AM J TROP MED HYG, V71, P153