Molecularly imprinted polymer cartridges coupled to high performance liquid chromatography (HPLC-UV) for simple and rapid analysis of fenthion in olive oil

被引：39

作者：

Bakas, Idriss ^{[1
,2
]}

Ben Oujji, Najwa ^{[1
,2
]}

Istamboulie, Georges ^{[1
]}

Piletsky, Sergey ^{[3
]}

Piletska, Elena ^{[3
]}

Ait-Addi, Elhabib ^{[2
]}

Ait-Ichou, Ihya ^{[2
]}

Noguer, Thierry ^{[1
]}

Rouillon, Regis ^{[1
]}

机构：

[1] Univ Perpignan, IMAGES, EA4218, F-66860 Perpignan, France

[2] Univ Ibn Zohr, Fac Sci, Lab AQUAMAR, Equipe Mat Photocatalyse & Environm, Agadir, Morocco

[3] Univ Leicester, Coll Sci & Engn, Dept Chem, Leicester LE1 7RH, Leics, England

来源：

TALANTA | 2014年 / 125卷

关键词：

Molecular modelling; MIP; Solid phase extraction (SPE); Selective extraction; Olive oil; Fenthion; ORGANOPHOSPHORUS PESTICIDE-RESIDUES; SOLID-PHASE EXTRACTION; GAS-CHROMATOGRAPHY; GC-MS; METABOLITES; CLEANUP; SAMPLES; CONFIRMATION;

D O I：

10.1016/j.talanta.2014.03.020

中图分类号：

O65 [分析化学];

学科分类号：

070302 ; 081704 ;

摘要：

A combination of molecular modelling and a screening of the library of non-imprinted polymers (NIPs) was used to identify acrylamide as a functional monomer with high affinity towards fenthion, organophosphate insecticide, which is frequently used in the treatment of olives. A good correlation was found between the screening tests and modelling of monomer-template interactions performed using a computational approach. Acrylamide-based molecularly imprinted polymer (MIP) and non-imprinted polymer (NIP) were thermally synthesised in dimethyl formamide (porogen) using ethylene glycol dimethacrylate as a cross-linker and 1,1-azo-bis (isobutyronitrile) as an initiator. The chemical and physical properties of the prepared polymers were characterised. The binding of fenthion by the polymers was studied using solvents with different polarities. The developed MIP showed a high selectivity towards fenthion, compared to other organophosphates (dimethoate, methidathion malalthion), and allowed extraction of fenthion from olive oil samples with a recovery rate of about 96%. The extraction of fenthion using MIPs was much more effective than traditional C-18 reverse-phase solid phase extraction and allowed to achieve a low detection limit (LOD) (5 mu g L-1). (C) 2014 Elsevier B.V. All rights reserved.

引用

页码：313 / 318

页数：6

共 30 条

[11] Rapid GC-FPD determination of organophosphorus pesticide residues in Sicilian and Apulian olive oil [J].