Seroprevalence of Neospora caninum infection and associated risk factors in dairy cattle in Serbia

被引:8
作者
Klun, Ivana [1 ]
Cirkovic, Vladimir [1 ]
Maletic, Milan [2 ]
Bradonjic, Sinisa [3 ]
Djurkovic-Djakovic, Olgica [1 ]
机构
[1] Univ Belgrade, Ctr Excellence Food & Vector Borne Zoonoses, Natl Reference Lab Toxoplasmosis, Inst Med Res, Dr Subotica 4, Belgrade 11129, Serbia
[2] Univ Belgrade, Fac Vet Med, Dept Reprod Fertil & Artificial Inseminat, Bulevar Oslobodjenja 18, Belgrade 11000, Serbia
[3] Minist Agr Forestry & Water Management Serbia, Vet Directorate, Omladinskih Brigada 1, Belgrade 11000, Serbia
关键词
Neospora caninum; Seroprevalence; Risk factors; Dairy cattle; Serbia; DEFINITIVE HOSTS; BEEF-CATTLE; ABORTION; HERDS; COWS; PREVALENCE; VALIDATION; ANTIBODIES; DIAGNOSIS; HOLSTEIN;
D O I
10.1007/s00436-019-06307-9
中图分类号
R38 [医学寄生虫学]; Q [生物科学];
学科分类号
07 ; 0710 ; 09 ; 100103 ;
摘要
Neosporosis in cattle is a globally important disease, causing abortions and significant economic losses if epidemic abortions occur. In Serbia, however, studies of Neospora caninum infection in cattle are few and are based on limited samples and/or from limited areas. We thus performed a nationwide study to examine the seroprevalence of N. caninum infection in a sample of cows randomly selected from dairy farms in 12 epidemiological units from throughout Serbia, as well as the possible transmission risk factors. Sera from a total of 1496 cattle were tested by competitive ELISA, and N. caninum-specific antibodies were shown in 7.2% animals (95% confidence interval CI, 6.6-7.9%), ranging from 2.2 to 12% across the epidemiological units. At least one seropositive animal was detected on 10.7% (95% CI, 9.7-11.8%) of farms, with a range of 5.9-25.9%. Logistic regression analysis showed that the single risk factor for infection in individual animals was keeping cows in loose-stalls (OR=3.31, 95% CI=1.95-5.60, P<0.001). Risk factors for the presence of infection on farms also included housing in loose-stalls (OR=18.49, 95% CI=5.40-63.36, P<0.001), and herd size >100 animals (OR=24.08, 95% CI=3.85-150.50, P=0.001). In view of the relatively low prevalence of infection showed at both the individual and farm level, this is the perfect time to undertake appropriate preventive measures to improve animal health and reduce economic losses.
引用
收藏
页码:1875 / 1883
页数:9
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