Placental histopathology after Coxiella burnetii infection during pregnancy

被引:8
作者
Munster, J. M. [1 ]
Leenders, A. C. A. P. [2 ]
Hamilton, C. J. C. M. [3 ]
Hak, E. [4 ]
Aarnoudse, J. G. [1 ]
Timmer, A. [5 ]
机构
[1] Univ Groningen, Univ Med Ctr Groningen, Dept Obstet & Gynaecol, NL-9713 GZ Groningen, Netherlands
[2] Jeroen Bosch Hosp, Dept Med Microbiol & Infect Prevent, NL-5223 GZ Shertogenbosch, Netherlands
[3] Jeroen Bosch Hosp, Dept Obstet & Gynaecol, NL-5223 GZ Shertogenbosch, Netherlands
[4] Univ Groningen, Univ Ctr Pharm PharmacoEpidemiol & PharmacoEcon, NL-9713 AV Groningen, Netherlands
[5] Univ Groningen, Univ Med Ctr Groningen, Dept Pathol & Med Biol, NL-9713 GZ Groningen, Netherlands
关键词
Q fever; Coxiella burnetii; Asymptomatic; Placental histopathology; CHRONIC Q-FEVER; NETHERLANDS; OUTBREAK; THERAPY; WOMEN;
D O I
10.1016/j.placenta.2011.11.012
中图分类号
Q [生物科学];
学科分类号
07 ; 0710 ; 09 ;
摘要
Symptomatic and asymptomatic Coxiella burnetii infection during pregnancy have been associated with obstetric complications. We described placental histopathology and clinical outcome of five cases with asymptomatic C burnetii infection during pregnancy and compared these cases with four symptomatic cases from the literature. In contrast with the symptomatic cases, we did not observe necrosis or active inflammation in the placentas of the asymptomatic women. Obstetrical outcome was more favourable in the asymptomatic cases than in the symptomatic cases. Asymptomatic and symptomatic C. burnetii infection during pregnancy are different entities with respect to placental histopathology and the risk of obstetric complications. (C) 2011 Elsevier Ltd. All rights reserved.
引用
收藏
页码:128 / 131
页数:4
相关论文
共 20 条
[1]   T cells are essential for bacterial clearance, and gamma interferon, tumor necrosis factor alpha, and B cells are crucial for disease development in Coxiella burnetii infection in mice [J].
Andoh, Masako ;
Zhang, Guoquan ;
Russell-Lodrigue, Kasi E. ;
Shive, Heather R. ;
Weeks, Brad R. ;
Samuel, James E. .
INFECTION AND IMMUNITY, 2007, 75 (07) :3245-3255
[2]  
[Anonymous], 2010, ANN EP REP COMM DIS
[3]   CHRONIC Q-FEVER OF PREGNANCY PRESENTING AS COXIELLA-BURNETII PLACENTITIS - SUCCESSFUL OUTCOME FOLLOWING THERAPY WITH ERYTHROMYCIN AND RIFAMPIN [J].
BENTAL, T ;
FEJGIN, M ;
KEYSARY, A ;
RZOTKIEWICZ, S ;
ORON, C ;
NACHUM, R ;
BEYTH, Y ;
LANG, R .
CLINICAL INFECTIOUS DISEASES, 1995, 21 (05) :1318-1321
[4]   Managing Q fever during pregnancy: The benefits of long-term cotrimoxazole therapy [J].
Carcopino, Xavier ;
Raoult, Didier ;
Bretelle, Florence ;
Boubli, Leon ;
Stein, Andreas .
CLINICAL INFECTIOUS DISEASES, 2007, 45 (05) :548-555
[5]   Q-FEVER AND INTRAUTERINE DEATH [J].
FRIEDLAND, JS ;
JEFFREY, I ;
GRIFFIN, GE ;
BOOKER, M ;
COURTENAYEVANS, R .
LANCET, 1994, 343 (8892) :288-288
[6]  
Hansen MS, 2011, VET J 0201
[7]  
Hartzell JD, 2008, MAYO CLIN PROC, V83, P574, DOI 10.4065/83.5.574
[8]   Multigenotype Q Fever Outbreak, the Netherlands [J].
Klaassen, Corne H. W. ;
Nabuurs-Franssen, Marrigje H. ;
Tilburg, Jeroen J. H. C. ;
Hamans, Maurice A. W. M. ;
Horrevorts, Alphons M. .
EMERGING INFECTIOUS DISEASES, 2009, 15 (04) :613-614
[9]   Coxiella burnetii seropositivity in parturient women is associated with adverse pregnancy outcomes [J].
Langley, JM ;
Marrie, TJ ;
LeBlanc, JC ;
Almudevar, A ;
Resch, L ;
Raoult, D .
AMERICAN JOURNAL OF OBSTETRICS AND GYNECOLOGY, 2003, 189 (01) :228-232
[10]   Cost-effectiveness of a screening strategy for Q fever among pregnant women in risk areas: a clustered randomized controlled trial [J].
Munster, Janna M. ;
Leenders, Alexander C. A. P. ;
van der Hoek, Wim ;
Schneeberger, Peter M. ;
Rietveld, Ariene ;
Riphagen-Dalhuisen, Josien ;
Stolk, Ronald P. ;
Hamilton, Carl J. C. M. ;
de Vries, Esther ;
Meekelenkamp, Jamie ;
Lo-Ten-Foe, Jerome R. ;
Timmer, Albertus ;
De Jong-van den Berg, Lolkje T. W. ;
Aarnoudse, Jan G. ;
Hak, Eelko .
BMC WOMENS HEALTH, 2010, 10