Iodine-catalyzed synthesis of pyrrolo[1,2-a]quinazoline-3a-carboxylic acid derivatives in ionic liquids

被引：7

作者：

Zhang, Mei-Mei ^{[1
]}

Lu, Lian ^{[2
]}

Zhou, Yu-Jing ^{[2
]}

Wang, Xiang-Shan ^{[2
]}

机构：

[1] Jiangsu Normal Univ, Key Lab Biotechnol Med Plant Jiangsu Prov, Xuzhou 221116, Jiangsu, Peoples R China

[2] Jiangsu Normal Univ, Sch Chem & Chem Engn, Jiangsu Key Lab Green Synthet Chem Funct Mat, Xuzhou 221116, Jiangsu, Peoples R China

来源：

RESEARCH ON CHEMICAL INTERMEDIATES | 2013年 / 39卷 / 07期

基金：

中国国家自然科学基金;

关键词：

Pyrroloquinazoline; 2-aminobenzamide; Ionic liquid; Iodine; Synthesis; THROMBIN RECEPTOR ANTAGONIST; INHIBITION; EFFICIENT; AID;

D O I：

10.1007/s11164-012-0845-x

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

The iodine-catalyzed reaction of 2-aminobenzamide and 2-oxopentanedioic acid in ionic liquids is described in this paper. It gave 1,5-dioxo-1,2,3,3a,4,5-hexahydropyrrolo[1,2-a]quinazoline-3a-carboxylic acid derivatives in high yields. One of their structures was confirmed by X-ray diffraction analysis.

引用

页码：3327 / 3335

页数：9

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