Sexual reproduction in the opportunistic human pathogen Aspergillus terreus

被引:35
作者
Arabatzis, Michael [1 ]
Velegraki, Aristea [1 ]
机构
[1] Natl & Kapodistrian Univ Athens, Mycol Lab, Dept Microbiol, Sch Med, Athens 11528, Greece
关键词
Aspergillus terreus; heterothallism; sexual reproduction; teleomorph; FUNGAL-INFECTIONS; EPIDEMIOLOGY; ASCOCARPS;
D O I
10.3852/11-426
中图分类号
Q93 [微生物学];
学科分类号
071005 ; 100705 ;
摘要
Aspergillus terreus has a worldwide distribution in soil, constitutes the third most important cause of invasive aspergillosis in humans and is classically regarded as a strictly asexual species. Strains of A. terreus were characterized by ITS, beta-tubulin and calmodulin sequences. Mating type was identified by amplifying and sequencing MAT1-1 and MAT1-2 genes. One MAT1-2 strain produced hyphal masses when crossed with four MAT1-1 strains on mixed cereal agar after 3 wk at 37 C. Cleistothecia formed inside the hyphal masses and produced asci containing smooth-walled ascospores with an equatorial protuberance. This is the first report of sexual reproduction in A. terreus.
引用
收藏
页码:71 / 79
页数:9
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