Kinetic and Thermodynamic Studies of pH-Triggered Membrane Insertion of Diphtheria Toxin T-Domain

被引:0
|
作者
Kyrychenko, Alexander [1 ]
Rodnin, Mykola V. [1 ]
Posokhov, Yevgen O. [1 ]
Thoma, Anna [1 ]
Brettmann, Joshua [1 ]
Ladokhin, Alexey S. [1 ]
机构
[1] KUMC, Kansas City, KS USA
关键词
D O I
10.1016/j.bpj.2009.12.2640
中图分类号
Q6 [生物物理学];
学科分类号
071011 ;
摘要
引用
收藏
页码:485A / 485A
页数:1
相关论文
共 50 条
  • [1] pH-Triggered Conformational Switching along the Membrane Insertion Pathway of the Diphtheria Toxin T-Domain
    Ladokhin, Alexey S.
    TOXINS, 2013, 5 (08): : 1362 - 1380
  • [2] pH-Triggered Membrane Insertion Pathway of the Diphtheria Toxin T-Domain: 1. Insertion/Refolding Intermediate
    Kyrychenko, Alexander
    Rodnin, Mykola V.
    Posokhov, Yevgen O.
    Ladokhin, Alexey S.
    BIOPHYSICAL JOURNAL, 2009, 96 (03) : 433A - 433A
  • [3] pH-Triggered Membrane Insertion Pathway of the Diphtheria Toxin T-Domain: 2. Role of Histidines
    Rodnin, Mykola V.
    Kyrychenko, Alexander
    Posokhov, Yevgen O.
    Brettmann, Joshua
    Thoma, Anna
    Ladokhin, Alexey S.
    BIOPHYSICAL JOURNAL, 2009, 96 (03) : 433A - 433A
  • [4] Thermodynamic and Kinetic Analysis of Membrane Protein Insertion: Case of Diphtheria Toxin T-Domain
    Ladokhin, Alexey S.
    Brettmann, Joshua
    Kyrychenko, Alexander
    Posokhov, Yevgen O.
    Rodnin, Mykola V.
    Thoma, Anna
    FASEB JOURNAL, 2010, 24
  • [5] Thermodynamics of Membrane Insertion and Refolding of the Diphtheria Toxin T-Domain
    Vargas-Uribe, Mauricio
    Rodnin, Mykola V.
    Ojemalm, Karin
    Holgado, Aurora
    Kyrychenko, Alexander
    Nilsson, IngMarie
    Posokhov, Yevgen O.
    Makhatadze, George
    von Heijne, Gunnar
    Ladokhin, Alexey S.
    JOURNAL OF MEMBRANE BIOLOGY, 2015, 248 (03): : 383 - 394
  • [6] Thermodynamics of Membrane Insertion and Refolding of the Diphtheria Toxin T-Domain
    Mauricio Vargas-Uribe
    Mykola V. Rodnin
    Karin Öjemalm
    Aurora Holgado
    Alexander Kyrychenko
    IngMarie Nilsson
    Yevgen O. Posokhov
    George Makhatadze
    Gunnar von Heijne
    Alexey S. Ladokhin
    The Journal of Membrane Biology, 2015, 248 : 383 - 394
  • [7] pH-Triggered Conformational Switching of the Diphtheria Toxin T-Domain: The Roles of N-Terminal Histidines
    Kurnikov, Igor V.
    Kyrychenko, Alexander
    Flores-Canales, Jose C.
    Rodnin, Mykola V.
    Simakov, Nikolay
    Vargas-Uribe, Mauricio
    Posokhov, Yevgen O.
    Kurnikova, Maria
    Ladokhin, Alexey S.
    JOURNAL OF MOLECULAR BIOLOGY, 2013, 425 (15) : 2752 - 2764
  • [8] Kinetic Intermediate Reveals Staggered pH-Dependent Transitions along the Membrane Insertion Pathway of the Diphtheria Toxin T-Domain
    Kyrychenko, Alexander
    Posokhov, Yevgen O.
    Rodnin, Mykola V.
    Ladokhin, Alexey S.
    BIOCHEMISTRY, 2009, 48 (32) : 7584 - 7594
  • [9] pH-Induced Reorganization and Membrane Insertion of the Diphtheria Toxin T-Domain Studied by Spr and Neutron Reflectometry
    Eells, Rebecca
    Heinirch, Frank
    Loesche, Mathias
    Rodnin, Mykola V.
    Ladokhin, Alexey S.
    BIOPHYSICAL JOURNAL, 2015, 108 (02) : 557A - 557A
  • [10] Multiscale Simulations of Diphtheria Toxin T-Domain Membrane Association
    Flores-Canales, Jose C.
    Ladokhin, Alexey S.
    Kurnikova, Maria
    BIOPHYSICAL JOURNAL, 2014, 106 (02) : 441A - 441A