Olanzapine for psychosis in patients with Parkinson's disease with and without dementia

被引:50
作者
Aarsland, D
Larsen, JP
Lim, NG
Tandberg, E
机构
[1] Rogaland Psychiat Hosp, Sect Geriatr Psychiat, N-4004 Stavanger, Norway
[2] Cent Hosp Rogaland, Sect Geriatr Psychiat, Stavanger, Norway
关键词
D O I
10.1176/jnp.11.3.392
中图分类号
R74 [神经病学与精神病学];
学科分类号
摘要
Twenty-one patients with Parkinson's disease and psychosis were included in an open-label 8-week trial of olanzapine. Eight subjects had dementia. Six subjects (29%) discontinued treatment prematurely because of drowsiness. Delusions and hallucinations improved significantly, and 80% were rated as much or very much improved. There was no worsening of parkinsonism or cognition.
引用
收藏
页码:392 / 394
页数:3
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