Conversion dependence of enantioselective hydrogenation of (E)-alpha-phenylcinnamic acid on cinchonidine-modified Pd/TiO2 catalyst

被引：84

作者：

Nitta, Y

Kobiro, K

机构：

[1] Niihama Natl. College of Technology, Niihama, Ehime 792, Yagumo-cho

来源：

CHEMISTRY LETTERS | 1996年 / 10期

关键词：

D O I：

10.1246/cl.1996.897

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

The enantioselectivity of a cinchonidine-modified Pd/TiO2 catalyst varied with the extent of conversion in the hydrogenation of (E)-alpha-phenylcinnamic acid. The incremental enantioselectivity reached a maximum at an early stage of the reaction. Under optimized reaction conditions, optical yields of up to 72%e.e. of (S)-(+)-2,3-diphenylpropionic acid were obtained at 100% conversion.

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页码：897 / 898

页数：2

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