Calixarene Derivatives for (Nano)Biotechnologies

被引：7

作者：

Rodik, Roman ^{[1
]}

Poberezhnyk, Mykola ^{[1
]}

Kalchenko, Vitaly ^{[1
]}

机构：

[1] Natl Acad Sci Ukraine, Inst Organ Chem, UA-02660 Kiev, Ukraine

来源：

MACROHETEROCYCLES | 2017年 / 10卷 / 04期

关键词：

Calixarenes; nanobiotechonogies; intracellular transport; phosphatases inhibitors; DNA transfection; bio-imaging; METHYLENEBISPHOSPHONIC ACIDS; NANOPARTICLES; INHIBITION; MICELLES;

D O I：

10.6060/mhc171150k

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

This review summarizes the author's research in the field of bio-medical application of modified calixarenes as well as their nano-associates. The paper includes results of design and investigation of the calixarenes as intracellular transport modulators of Ca and Na cations, as well as effective and selective phosphatases inhibitors. The antibacterial and anticoagulant properties of series water-soluble positively or negatively charged calixarenes are described. Also, utilization of calixarenes for hierarchical formation of nanoparticles for nanobiotechnological application (DNA transfection and bio-imaging) is discussed.

引用

页码：421 / 431

页数：11

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