Human-to-Human Transmission of Severe Fever With Thrombocytopenia Syndrome Bunyavirus Through Contact With Infectious Blood

被引：290

作者：

Tang, Xiaoyan ^{[1
]}

Wu, Weili ^{[2
]}

Wang, Haifeng ^{[1
]}

Du, Yanhua ^{[1
]}

Liu, Licheng ^{[3
,6
]}

Kang, Kai ^{[1
]}

Huang, Xueyong ^{[1
]}

Ma, Hong ^{[1
]}

Mu, Feng ^{[6
]}

Zhang, Shiqiang ^{[7
]}

Zhao, Guohua ^{[7
]}

Cui, Ning ^{[4
]}

Zhu, Bao-Ping ^{[5
]}

You, Aiguo ^{[1
]}

Chen, Haomin ^{[1
]}

Liu, Guohua ^{[1
]}

Chen, Weijun ^{[2
,3
,5
,6
]}

Xu, Bianli ^{[1
]}

机构：

[1] Ctr Dis Control & Prevent Henan Prov, Zhengzhou, Peoples R China

[2] Chinese Acad Sci, Key Lab Genome Sci & Informat, Beijing Inst Genom, Beijing, Peoples R China

[3] Acad Mil Med Sci, State Key Lab Pathogen & Biosecur, Inst Microbiol & Epidemiol, Beijing, Peoples R China

[4] Chinese Filed Epidemiol Training Program, Beijing, Peoples R China

[5] Beijing Genom Inst Wuhan, Wuhan 430075, Peoples R China

[6] Ctr Dis Control & Prevent Xinyang City, Xinyang City, Peoples R China

[7] 154th Hosp, Xinyang, Peoples R China

来源：

JOURNAL OF INFECTIOUS DISEASES | 2013年 / 207卷 / 05期

关键词：

severe fever with thrombocytopenia syndrome virus (SFTSV); human-to-human transmission; blood; RISK-FACTOR; CHINA;

D O I：

10.1093/infdis/jis748

中图分类号：

R392 [医学免疫学]; Q939.91 [免疫学];

学科分类号：

100102 ;

摘要：

We investigated an outbreak of severe fever with thrombocytopenia syndrome (SFTS) that occurred during May and June 2010, to identify the mode of transmission. Contact with the index patient's blood was significantly associated with development of SFTS (P = .01, by the chi(2) test for linear trend); the frequency of contact with the index patient's blood increased the risk of SFTS in a dose-response manner (P = .03, by the chi(2) test for linear trend). We concluded that human-to-human transmission caused this cluster of cases.

引用

页码：736 / 739

页数：4

共 9 条

[1]

[Anonymous], 2008, GUID CONTR HUM GRAN

[2] A Family Cluster of Infections by a Newly Recognized Bunyavirus in Eastern China, 2007: Further Evidence of Person-to-Person Transmission [J].

Bao, Chang-jun ;

Guo, Xi-ling ;

Qi, Xian ;

Hu, Jian-li ;

Zhou, Ming-hao ;

Varma, Jay K. ;

Cui, Lun-biao ;

Yang, Hai-tao ;

Jiao, Yong-jun ;

Klena, John D. ;

Li, Lu-xun ;

Tao, Wen-yuan ;

Li, Xian ;

Chen, Yin ;

Zhu, Zheng ;

Xu, Ke ;

Shen, Ai-hua ;

Wu, Tao ;

Peng, Hai-yan ;

Li, Zhi-feng ;

Shan, Jun ;

Shi, Zhi-yang ;

Wang, Hua .

CLINICAL INFECTIOUS DISEASES, 2011, 53 (12) :1208-1214

[3]

Bao CJ, 2011, NEW ENGL J MED, V365, P862, DOI 10.1056/NEJMc1106000

[4]

Bianli X, 2011, PLOS PATHOG, V7

[5] Early Use of Glucocorticoids Was a Risk Factor for Critical Disease and Death From pH1N1 Infection [J].

Han, Ke ;

Ma, Huilai ;

An, Xiangdong ;

Su, Yang ;

Chen, Jing ;

Lian, Zhiyong ;

Zhao, JinHui ;

Zhu, Bao-Ping ;

Fontaine, Robert E. ;

Feng, Zijian ;

Zeng, Guang .

CLINICAL INFECTIOUS DISEASES, 2011, 53 (04) :326-333

[6] Glucocorticoid and Pyrazolone Treatment of Acute Fever is a Risk Factor for Critical and Life-Threatening Human Enterovirus 71 Infection During an Outbreak in China, 2008 [J].

Ma, HuiLai ;

He, Fan ;

Wan, JunFeng ;

Jin, DongHui ;

Zhu, LiYe ;

Liu, XuXiang ;

Liu, QiQuan ;

Zhang, GuoHong ;

Ding, ZhenTao ;

Fontaine, Robert E. ;

Zhu, Bao-Ping ;

Jian, HaiHui ;

Zhang, LiJie ;

Xu, WenBo ;

Zeng, Guang .

PEDIATRIC INFECTIOUS DISEASE JOURNAL, 2010, 29 (06) :524-529

[7]

Shunan G, 2005, CHIN J INFORM TRADIT, V22, P38

[8]

Siegel JD., 2019, 2007 guideline for isolation precautions: Preventing transmission of infectious agents in healthcare settings

[9] Fever with Thrombocytopenia Associated with a Novel Bunyavirus in China [J].

Yu, Xue-Jie ;

Liang, Mi-Fang ;

Zhang, Shou-Yin ;

Liu, Yan ;

Li, Jian-Dong ;

Sun, Yu-Lan ;

Zhang, Lihong ;

Zhang, Quan-Fu ;

Popov, Vsevolod L. ;

Li, Chuan ;

Qu, Jing ;

Li, Qun ;

Zhang, Yan-Ping ;

Hai, Rong ;

Wu, Wei ;

Wang, Qin ;

Zhan, Fa-Xian ;

Wang, Xian-Jun ;

Kan, Biao ;

Wang, Shi-Wen ;

Wan, Kang-Lin ;

Jing, Huai-Qi ;

Lu, Jin-Xin ;

Yin, Wen-Wu ;

Zhou, Hang ;

Guan, Xu-Hua ;

Liu, Jia-Fa ;

Bi, Zhen-Qiang ;

Liu, Guo-Hua ;

Ren, Jun ;

Wang, Hua ;

Zhao, Zhuo ;

Song, Jing-Dong ;

He, Jin-Rong ;

Wan, Tao ;

Zhang, Jing-Shan ;

Fu, Xiu-Ping ;

Sun, Li-Na ;

Dong, Xiao-Ping ;

Feng, Zi-Jian ;

Yang, Wei-Zhong ;

Hong, Tao ;

Zhang, Yu ;

Walker, David H. ;

Wang, Yu ;

Li, De-Xin .

NEW ENGLAND JOURNAL OF MEDICINE, 2011, 364 (16) :1523-1532

← 1 →