Prevention and Treatment of Venous Thromboembolism in Pregnancy

被引:22
作者
James, Andra H. [1 ]
机构
[1] Duke Univ, Med Ctr, Dept Obstet & Gynecol, Div Maternal Fetal Med, Durham, NC 27710 USA
关键词
thromboembolism; pregnancy; postpartum; anticoagulation; heparin; MOLECULAR-WEIGHT HEPARIN; DEEP-VEIN THROMBOSIS; PULMONARY-EMBOLISM; RISK-FACTORS; UNFRACTIONATED HEPARIN; ANTICOAGULANT-THERAPY; POSTPARTUM PERIOD; UNITED-STATES; HEART-VALVES; BED REST;
D O I
10.1097/GRF.0b013e31825cfe7b
中图分类号
R71 [妇产科学];
学科分类号
100211 ;
摘要
During pregnancy, women have a 4- to 5-fold increased risk of thromboembolism. Candidates for anticoagulation in pregnancy include women with current thrombosis, a history of thrombosis, risk factors for postpartum thrombosis, and some women with thrombophilia and a history of poor pregnancy outcome. Although, there are no large trials of anticoagulants in pregnancy and recommendations for their use are based on case series and the opinion of experts, observational studies demonstrate the benefit of heparins in reducing the risk of recurrent thromboembolism in pregnancy. A practical approach to the prevention and treatment of thromboembolism in pregnancy is outlined.
引用
收藏
页码:774 / 787
页数:14
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