Pd-catalyzed double C-H bond activation of diaryl ketones for the synthesis of fluorenones

被引：105

作者：

Gandeepan, Parthasarathy ^{[1
]}

Hung, Chen-Hsun ^{[1
]}

Cheng, Chien-Hong ^{[1
]}

机构：

[1] Natl Tsing Hua Univ, Dept Chem, Hsinchu 30013, Taiwan

来源：

CHEMICAL COMMUNICATIONS | 2012年 / 48卷 / 75期

关键词：

ALDOXIME ETHERS; RING-CLOSURE; ARYL HALIDES; PALLADIUM; OXIDATION; ANNULATION; ARYLATION; FUNCTIONALIZATION; FLUOREN-9-ONES; DERIVATIVES;

D O I：

10.1039/c2cc34344d

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

An efficient synthesis of fluorenones from diaryl ketones by Pd-catalyzed oxidative cyclization is described. A possible mechanism involving a carbonyl group assisted ortho-C-H activation and cyclometalation followed by a second C-H activation to form a six-membered palladacycle and reductive elimination is proposed.

引用

页码：9379 / 9381

页数：3

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