Discrimination of lymph node metastases using desorption electrospray ionisation-mass spectrometry imaging

被引:35
作者
Abbassi-Ghadi, N. [1 ]
Veselkov, K. [1 ]
Kumar, S. [1 ]
Huang, J. [1 ]
Jones, E. [1 ]
Strittmatter, N. [1 ]
Kudo, H. [2 ]
Goldin, R. [2 ]
Takats, Z. [1 ]
Hanna, G. B. [1 ]
机构
[1] Univ London Imperial Coll Sci Technol & Med, St Marys Hosp, Dept Surg & Canc, London W2 1NY, England
[2] Univ London Imperial Coll Sci Technol & Med, Ctr Pathol, London W2 1NY, England
基金
欧洲研究理事会;
关键词
D O I
10.1039/c3cc48927b
中图分类号
O6 [化学];
学科分类号
0703 ;
摘要
Desorption electrospray ionisation mass spectrometry imaging (DESI-MSI) has been used for the identification of cancer within lymph nodes with accurate spatial distribution in comparison to gold standard matched immuno-histopathological images. The metabolic profile of the cancerous lymph nodes was similar to that of the primary tumour site.
引用
收藏
页码:3661 / 3664
页数:4
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