Multifunctionalized Sequence-Defined Oligomers from a Single Building Block

被引：186

作者：

Espeel, Pieter ^{[1
]}

Carrette, Lieselot L. G. ^{[2
]}

Bury, Katarzyna ^{[1
]}

Capenberghs, Sven ^{[1
]}

Martins, Jose C. ^{[3
]}

Du Prez, Filip E. ^{[1
]}

Madder, Annemieke ^{[2
]}

机构：

[1] Univ Ghent, Dept Organ Chem, Polymer Chem Res Grp, B-9000 Ghent, Belgium

[2] Univ Ghent, Dept Organ Chem, Organ & Biomimet Chem Res Grp, B-9000 Ghent, Belgium

[3] Univ Ghent, Dept Organ Chem, NMR & Struct Anal Res Grp, B-9000 Ghent, Belgium

来源：

ANGEWANDTE CHEMIE-INTERNATIONAL EDITION | 2013年 / 52卷 / 50期

关键词：

chemoselectivity; sequence-defined oligomers; solid-phase synthesis; synthetic methods; thiolactone; PHASE PEPTIDE-SYNTHESIS; PRECISION POLYMERS; SYNTHETIC-POLYMERS; ONE-POT; POLYMERIZATION; MONOMER; COVALENT; AMINE; CLICK; THIOL;

D O I：

10.1002/anie.201307439

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

Another link in the chain: A thiolactone-based approach for the preparation of multifunctionalized sequence-defined oligomeric structures on solid support was established. The iterative aminolysis/chain extension method with a single building block and a variety of commercial amines allowed for the protecting group free synthesis of various oligomeric motifs with a unique backbone and a preprogrammed organization of side chain functionalities. © 2013 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim.

引用

页码：13261 / 13264

页数：4

共 61 条

[51] A facile procedure for controlling monomer sequence distribution in radical chain polymerizations [J].

Pfeifer, Sebastian ;

Lutz, Jean-Francois .

JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, 2007, 129 (31) :9542-+

[52] Tailor-Made Soluble Polymer Supports: Synthesis of a Series of ATRP Initiators Containing Labile Wang Linkers [J].

Pfeifer, Sebastian ;

Lutz, Jean-Francois .

MACROMOLECULAR CHEMISTRY AND PHYSICS, 2010, 211 (08) :940-947

[53] Liquid-Phase Synthesis of Block Copolymers Containing Sequence-Ordered Segments [J].

Pfeifer, Sebastian ;

Zarafshani, Zoya ;

Badi, Nezha ;

Lutz, Jean-Francois .

JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, 2009, 131 (26) :9195-+

[54] Development of a Library of N-Substituted Maleimides for the Local Functionalization of Linear Polymer Chains [J].

Pfeifer, Sebastian ;

Lutz, Jean-Francois .

CHEMISTRY-A EUROPEAN JOURNAL, 2008, 14 (35) :10949-10957

[55] One-Pot Double Modification of p(NIPAAm): A Tool for Designing Tailor-Made Multiresponsive Polymers [J].

Reinicke, Stefan ;

Espeel, Pieter ;

Stamenovic, Milan M. ;

Du Prez, Filip E. .

ACS MACRO LETTERS, 2013, 2 (06) :539-543

[56]

Schmidt BVKJ, 2011, NAT CHEM, V3, P234, DOI [10.1038/NCHEM.964, 10.1038/nchem.964]

[57] Straightforward synthesis of functionalized cyclic polymers in high yield via RAFT and thiolactone-disulfide chemistry [J].

Stamenovic, Milan M. ;

Espeel, Pieter ;

Baba, Eisuke ;

Yamamoto, Takuya ;

Tezuka, Yasuyuki ;

Du Prez, Filip E. .

POLYMER CHEMISTRY, 2013, 4 (01) :184-193

[58] Single-Chain Folding of Polymers for Catalytic Systems in Water [J].

Terashima, Takaya ;

Mes, Tristan ;

De Greef, Tom F. A. ;

Gillissen, Martijn A. J. ;

Besenius, Pol ;

Palmans, Anja R. A. ;

Meijer, E. W. .

JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, 2011, 133 (13) :4742-4745

[59] Synthesis of sequence-ordered polymers via sequential addition of monomers in one pot [J].

Yan, Jun-Jie ;

Wang, Di ;

Wu, De-Cheng ;

You, Ye-Zi .

CHEMICAL COMMUNICATIONS, 2013, 49 (54) :6057-6059

[60]

Zhang Q., 2013, ANGEW CHEM, V125, P4531

← 1 2 3 4 5 6 7 →