Targeting cancer stem cells by a novel anti-frizzled antibody inhibits pancreatic tumor growth and induces differentiation

被引:1
|
作者
Yen, Wan-Ching [1 ]
Fischer, Marcus [1 ]
Lewicki, John [1 ]
Gurney, Austin [1 ]
Hoey, Timothy [1 ]
机构
[1] Oncomed Pharmaceut Inc, Redwood City, CA USA
关键词
D O I
10.1158/1538-7445.AM2011-973
中图分类号
R73 [肿瘤学];
学科分类号
100214 ;
摘要
973
引用
收藏
页数:2
相关论文
共 50 条
  • [41] Differentiation of adipose tissue derived stem cells to natural killer cells having anti-tumor activities in vitro in pancreatic cancer
    Karlitepe, A.
    Ercan, G.
    Vatansever, S.
    Kabadayi, H.
    Gunduz, C.
    Avci, C.
    FEBS JOURNAL, 2016, 283 : 92 - 92
  • [42] Tributyrin, a butyrate precursor, impairs growth and induces apoptosis and differentiation in pancreatic cancer cells
    Gaschott, T
    Maassen, CU
    Stein, J
    ANTICANCER RESEARCH, 2001, 21 (4A) : 2815 - 2819
  • [43] A novel triazolonaphthalimide induces apoptosis and inhibits tumor growth by targeting DNA and DNA-associated processes
    Ji, Liyan
    Yang, Simin
    Li, Shasha
    Liu, Shan
    Tang, Shunan
    Liu, Zhongqiu
    Meng, Xiangbao
    Yu, Siwang
    ONCOTARGET, 2017, 8 (23) : 37394 - 37408
  • [44] Targeting ITGA5 in pancreatic stellate cells as a novel strategy to restrain pancreatic tumor growth
    Kuninty, Praneeth
    de Geus, Sanne
    Bansal, Ruchi
    Schnittert, Jonas
    Kuppen, Peter
    Vahrmeijer, Alexander
    Ostman, Arne
    Sier, Cornelies
    Prakash, Jai
    MOLECULAR CANCER THERAPEUTICS, 2018, 17 (01)
  • [45] Monensin inhibits cell proliferation and tumor growth of chemo-resistant pancreatic cancer cells by targeting the EGFR signaling pathway
    Wang, Xin
    Wu, Xingye
    Zhang, Zhonglin
    Ma, Chao
    Wu, Tingting
    Tang, Shengli
    Zeng, Zongyue
    Huang, Shifeng
    Gong, Cheng
    Yuan, Chengfu
    Zhang, Linghuan
    Feng, Yixiao
    Huang, Bo
    Liu, Wei
    Zhang, Bo
    Shen, Yi
    Luo, Wenping
    Wang, Xi
    Liu, Bo
    Lei, Yan
    Ye, Zhenyu
    Zhao, Ling
    Cao, Daigui
    Yang, Lijuan
    Chen, Xian
    Haydon, Rex C.
    Luu, Hue H.
    Peng, Bing
    Liu, Xubao
    He, Tong-Chuan
    SCIENTIFIC REPORTS, 2018, 8
  • [46] Monensin inhibits cell proliferation and tumor growth of chemo-resistant pancreatic cancer cells by targeting the EGFR signaling pathway
    Xin Wang
    Xingye Wu
    Zhonglin Zhang
    Chao Ma
    Tingting Wu
    Shengli Tang
    Zongyue Zeng
    Shifeng Huang
    Cheng Gong
    Chengfu Yuan
    Linghuan Zhang
    Yixiao Feng
    Bo Huang
    Wei Liu
    Bo Zhang
    Yi Shen
    Wenping Luo
    Xi Wang
    Bo Liu
    Yan Lei
    Zhenyu Ye
    Ling Zhao
    Daigui Cao
    Lijuan Yang
    Xian Chen
    Rex C. Haydon
    Hue H. Luu
    Bing Peng
    Xubao Liu
    Tong-Chuan He
    Scientific Reports, 8
  • [47] Digalloylresveratrol, a novel resveratrol analog inhibits the growth of human pancreatic cancer cells
    Philipp Saiko
    Geraldine Graser
    Benedikt Giessrigl
    Marie-Thérèse Steinmann
    Heike Schuster
    Andreas Lackner
    Michael Grusch
    Georg Krupitza
    Walter Jaeger
    Venkateswarlu Somepalli
    Trimurtulu Golakoti
    Monika Fritzer-Szekeres
    Thomas Szekeres
    Investigational New Drugs, 2013, 31 : 1115 - 1124
  • [48] Targeting of cancer stem cell marker EpCAM by bispecific antibody EpCAMxCD3 inhibits pancreatic carcinoma
    Salnikov, Alexei V.
    Groth, Ariane
    Apel, Anja
    Kallifatidis, Georgios
    Beckermann, Benjamin M.
    Khamidjanov, Akmal
    Ryschich, Eduard
    Buechler, Markus W.
    Herr, Ingrid
    Moldenhauer, Gerhard
    JOURNAL OF CELLULAR AND MOLECULAR MEDICINE, 2009, 13 (9B) : 4023 - 4033
  • [49] Digalloylresveratrol, a novel resveratrol analog inhibits the growth of human pancreatic cancer cells
    Saiko, Philipp
    Graser, Geraldine
    Giessrigl, Benedikt
    Steinmann, Marie-Therese
    Schuster, Heike
    Lackner, Andreas
    Grusch, Michael
    Krupitza, Georg
    Jaeger, Walter
    Somepalli, Venkateswarlu
    Golakoti, Trimurtulu
    Fritzer-Szekeres, Monika
    Szekeres, Thomas
    INVESTIGATIONAL NEW DRUGS, 2013, 31 (05) : 1115 - 1124
  • [50] A human monoclonal antibody to a novel ovarian cancer target inhibits tumor growth.
    Kanner, Steven B.
    Ganguly, Nandini
    Morrison, Kendall R.
    An, Zili
    Morrison, Karen J.
    Challita-Eid, Pia M.
    Raitano, Arthur B.
    Satpaev, Daulet
    Jia, Xiao-Chi
    Gudas, Jean M.
    Jakobovits, Aya
    MOLECULAR CANCER THERAPEUTICS, 2007, 6 (12) : 3450S - 3451S