Diabetes, obesity andCOVID-19: A complex interplay

被引:51
作者
Vas, Prashanth [1 ,2 ]
Hopkins, David [1 ,2 ,3 ]
Feher, Michael [4 ]
Rubino, Francesco [2 ,3 ,5 ]
Whyte, Martin B. [1 ,2 ,6 ]
机构
[1] Kings Coll NHS Fdn Trust, Dept Diabet, London, England
[2] King's Hlth Partners, Inst Diabet Endocrinol & Obes, London, England
[3] Kings Coll London, Sch Life Course Sci, Dept Diabet, London, England
[4] Univ Oxford, Nuffield Dept Primary Care Hlth Sci, Oxford, England
[5] Kings Coll Hosp London, Bariatr & Metab Surg, London, England
[6] Univ Surrey, Dept Clin & Expt Med, Guildford GU2 7YW, Surrey, England
关键词
COVID-19; MORTALITY; CORONAVIRUS; SEVERITY; DISEASE; INFECTION; MELLITUS; OUTCOMES; RISK;
D O I
10.1111/dom.14134
中图分类号
R5 [内科学];
学科分类号
1002 ; 100201 ;
摘要
With the accumulation of observational data showing an association of metabolic co-morbidities with adverse outcomes from COVID-19, there is a need to disentangle the contributions of pre-existing macro- and microvascular disease, obesity and glycaemia. This article outlines the complex mechanistic and clinical interplay between diabetes and COVID-19, the clinical and research questions which arise from this relationship, and the types of studies needed to answer those questions. The authors are clinicians and academics working in diabetes and obesity medicine, but the article is pitched to an audience of generalists with clinical experience of or interest in the management of COVID-19.
引用
收藏
页码:1892 / 1896
页数:5
相关论文
共 56 条
[1]   Prevalence and Outcomes of Acute Ischemic Stroke Among Patients ≤50 Years of Age With Laboratory Confirmed COVID-19 Infection [J].
Annie, Frank ;
Bates, Mark C. ;
Nanjundappa, Aravinda ;
Bhatt, Deepak L. ;
Alkhouli, Mohamad .
AMERICAN JOURNAL OF CARDIOLOGY, 2020, 130 :169-170
[2]   Differentiating COVID-19 Pneumonia From Acute Respiratory Distress Syndrome and High Altitude Pulmonary Edema Therapeutic Implications [J].
Archer, Stephen L. ;
Sharp, Willard W. ;
Weir, E. Kenneth .
CIRCULATION, 2020, 142 (02) :101-104
[3]  
Barron EBC, TYPE 1 TYPE 2 DIABET
[4]   Practical recommendations for the management of diabetes in patients with COVID-19 [J].
Bornstein, Stefan R. ;
Rubino, Francesco ;
Khunti, Kamlesh ;
Mingrone, Geltrude ;
Hopkins, David ;
Birkenfeld, Andreas L. ;
Boehm, Bernhard ;
Amiel, Stephanie ;
Holt, Richard I. G. ;
Skyler, Jay S. ;
DeVries, J. Hans ;
Renard, Eric ;
Eckel, Robert H. ;
Zimmet, Paul ;
George Alberti, Kurt ;
Vidal, Josep ;
Geloneze, Bruno ;
Chan, Juliana C. ;
Ji, Linong ;
Ludwig, Barbara .
LANCET DIABETES & ENDOCRINOLOGY, 2020, 8 (06) :546-550
[5]   Endocrine and metabolic link to coronavirus infection [J].
Bornstein, Stefan R. ;
Dalan, Rinkoo ;
Hopkins, David ;
Mingrone, Geltrude ;
Boehm, Bernhard O. .
NATURE REVIEWS ENDOCRINOLOGY, 2020, 16 (06) :297-298
[6]   Risk of Infection in Type 1 and Type 2 Diabetes Compared With the General Population: A Matched Cohort Study [J].
Carey, Iain M. ;
Critchley, Julia A. ;
DeWilde, Stephen ;
Harris, Tess ;
Hosking, Fay J. ;
Cook, Derek G. .
DIABETES CARE, 2018, 41 (03) :513-521
[7]   Phenotypic characteristics and prognosis of inpatients with COVID-19 and diabetes: the CORONADO study [J].
Cariou, Bertrand ;
Hadjadj, Samy ;
Wargny, Matthieu ;
Pichelin, Matthieu ;
Al-Salameh, Abdallah ;
Allix, Ingrid ;
Amadou, Coralie ;
Arnault, Gwenaelle ;
Baudoux, Florence ;
Bauduceau, Bernard ;
Borot, Sophie ;
Bourgeon-Ghittori, Muriel ;
Bourron, Olivier ;
Boutoille, David ;
Cazenave-Roblot, France ;
Chaumeil, Claude ;
Cosson, Emmanuel ;
Coudol, Sandrine ;
Darmon, Patrice ;
Disse, Emmanuel ;
Ducet-Boiffard, Amelie ;
Gaborit, Benedicte ;
Joubert, Michael ;
Kerlan, Veronique ;
Laviolle, Bruno ;
Marchand, Lucien ;
Meyer, Laurent ;
Potier, Louis ;
Prevost, Gaetan ;
Riveline, Jean-Pierre ;
Robert, Rene ;
Saulnier, Pierre-Jean ;
Sultan, Ariane ;
Thebaut, Jean-Francois ;
Thivolet, Charles ;
Tramunt, Blandine ;
Vatier, Camille ;
Roussel, Ronan ;
Gautier, Jean-Francois ;
Gourdy, Pierre .
DIABETOLOGIA, 2020, 63 (08) :1500-1515
[8]   Why is hyperglycaemia worseningCOVID-19 and its prognosis? [J].
Ceriello, Antonio ;
De Nigris, Valeria ;
Prattichizzo, Francesco .
DIABETES OBESITY & METABOLISM, 2020, 22 (10) :1951-1952
[9]   Diabetic ketoacidosis precipitated by Covid-19 in a patient with newly diagnosed diabetes mellitus [J].
Chee, Ying Jie ;
Ng, Shereen Jia Huey ;
Yeoh, Ester .
DIABETES RESEARCH AND CLINICAL PRACTICE, 2020, 164
[10]   Preliminary Estimates of the Prevalence of Selected Underlying Health Conditions Among Patients with Coronavirus Disease 2019-United States, February 12-March 28, 2020 [J].
Chow, Nancy ;
Fleming-Dutra, Katherine ;
Gierke, Ryan ;
Hall, Aron ;
Hughes, Michelle ;
Pilishvili, Tamara ;
Ritchey, Matthew ;
Roguski, Katherine ;
Skoff, Tami ;
Ussery, Emily .
MMWR-MORBIDITY AND MORTALITY WEEKLY REPORT, 2020, 69 (13) :382-386